CHEBI:747163 - Remodelin

ChEBI IDCHEBI:747163
ChEBI NameRemodelin
Stars
DefinitionRemodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model.
Last Modified12 January 2026
Submittercyan
FormulaC15H14N4S
Net Charge0
Average Mass282.372
Monoisotopic Mass282.09392
ChEBI Ontology
Outgoing Relation(s)
Remodelin (CHEBI:747163) is a organic molecular entity (CHEBI:50860)
Registry NumbersSources
CAS:949912-58-7CAS