EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:747163 |
| ChEBI Name | Remodelin |
| Stars | |
| Definition | Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model. |
| Last Modified | 12 January 2026 |
| Submitter | cyan |
| Formula | C15H14N4S |
| Net Charge | 0 |
| Average Mass | 282.372 |
| Monoisotopic Mass | 282.09392 |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Remodelin (CHEBI:747163) is a organic molecular entity (CHEBI:50860) |
| Registry Numbers | Sources |
|---|---|
| CAS:949912-58-7 | CAS |