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CHEBI:747127 - gepotidacin

Default Structure
ChEBI IDCHEBI:747127
ChEBI Namegepotidacin
Stars
DefinitionA first-in-class triazaacenaphthylene antibiotic acting as topoisomerase II inhibitor and indicated for the treatment of female patients with uncomplicated urinary tract infections caused by susceptible microorganisms.
Last Modified20 April 2026
SubmitterAnneNiknejad
DownloadsMolfile
FormulaC24H28N6O3
Net Charge0
Average Mass448.527
Monoisotopic Mass448.22229
SMILESO=c1ccc2ncc(=O)n3c2n1C[C@H]3CN1CCC(NCc2cc3c(cn2)OCCC3)CC1
InChIInChI=1S/C24H28N6O3/c31-22-4-3-20-24-29(22)15-19(30(24)23(32)13-27-20)14-28-7-5-17(6-8-28)25-11-18-10-16-2-1-9-33-21(16)12-26-18/h3-4,10,12-13,17,19,25H,1-2,5-9,11,14-15H2/t19-/m1/s1
InChIKeyPZFAZQUREQIODZ-LJQANCHMSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
Application:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
ChEBI Ontology
Outgoing Relation(s)
gepotidacin (CHEBI:747127) has role antibacterial agent (CHEBI:33282)
gepotidacin (CHEBI:747127) has role antiinfective agent (CHEBI:35441)
gepotidacin (CHEBI:747127) is a aminopiperidine (CHEBI:48588)
gepotidacin (CHEBI:747127) is a organic heterotricyclic compound (CHEBI:26979)
gepotidacin (CHEBI:747127) is a pyranopyridine (CHEBI:38192)
gepotidacin (CHEBI:747127) is a secondary amino compound (CHEBI:50995)
gepotidacin (CHEBI:747127) is a tertiary amino compound (CHEBI:50996)
INNs  Source
gepotidacinaWHO MedNet
gepotidacineWHO MedNet
Synonyms  Source
GepotidacinChEMBL
GSK 2140944CAS
GSK-2140944ChEMBL
GSK2140944ChEMBL
Manual XrefsDatabases
D10878KEGG DRUG
GepotidacinWikipedia
Registry NumbersSources
CAS:1075236-89-3CAS
Citations