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CHEBI:746967 - FB23-2

Default Structure
ChEBI IDCHEBI:746967
ChEBI NameFB23-2
Stars
DefinitionA hydroxamic acid resulting from the formal condensation of the carboxy group of 2-[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]benzoic acid with the amino group of hydroxylamine. It is an inhibitor of mRNA N6-methyladenosine (m6A) demethylase FTO (IC50 = 2.6 μM) that exhibits anti-proliferation activity.
Last Modified15 April 2026
Submittercyan
DownloadsMolfile
FormulaC18H15Cl2N3O3
Net Charge0
Average Mass392.242
Monoisotopic Mass391.04905
SMILESCc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(=O)NO)c(Cl)c1
InChIInChI=1S/C18H15Cl2N3O3/c1-9-16(10(2)26-23-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(24)22-25/h3-8,21,25H,1-2H3,(H,22,24)
InChIKeyILHNIWOZZKIBNW-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
FB23-2 (CHEBI:746967) has role antineoplastic agent (CHEBI:35610)
FB23-2 (CHEBI:746967) has role apoptosis inducer (CHEBI:68495)
FB23-2 (CHEBI:746967) is a dichlorobenzene (CHEBI:23697)
FB23-2 (CHEBI:746967) is a hydroxamic acid (CHEBI:24650)
FB23-2 (CHEBI:746967) is a isoxazoles (CHEBI:55373)
FB23-2 (CHEBI:746967) is a secondary amino compound (CHEBI:50995)
IUPAC Name 
2-[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]-N-hydroxybenzamide
Synonym  Source
2-[[2,6-dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]-N-hydroxybenzamideChEBI
Registry NumbersSources
CAS:2243736-45-8ChEBI
Citations