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CHEBI:746962 - MRTX1133

ChEBI IDCHEBI:746962
ChEBI NameMRTX1133
Stars
Last Modified24 November 2025
SubmitterAdnan
DownloadsMolfile
FormulaC33H31F3N6O2
Net Charge0
Average Mass600.645
Monoisotopic Mass600.24606
SMILESC#Cc1c(F)ccc2cc(O)cc(-c3ncc4c(N5CC6CCC(C5)N6)nc(OC[C@@]56CCCN5C[C@H](F)C6)nc4c3F)c12
InChIInChI=1S/C33H31F3N6O2/c1-2-23-26(35)7-4-18-10-22(43)11-24(27(18)23)29-28(36)30-25(13-37-29)31(41-15-20-5-6-21(16-41)38-20)40-32(39-30)44-17-33-8-3-9-42(33)14-19(34)12-33/h1,4,7,10-11,13,19-21,38,43H,3,5-6,8-9,12,14-17H2/t19-,20?,21?,33+/m1/s1
InChIKeySCLLZBIBSFTLIN-IFMUVJFISA-N
Wikipedia
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
MRTX1133 (CHEBI:746962) has role antineoplastic agent (CHEBI:35610)
MRTX1133 (CHEBI:746962) is a naphthalenes (CHEBI:25477)
MRTX1133 (CHEBI:746962) is a pyridopyrimidine (CHEBI:38932)
IUPAC Name 
4-[4-(3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-{[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl]-5-ethynyl-6-fluoronaphthalen-2-ol
Synonyms  Source
MRTX 1133ChEBI
MRTX-1133ChEBI
Manual XrefsDatabases
MRTX1133Wikipedia
Registry NumbersSources
CAS:2621928-55-8ChEBI
Citations