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CHEBI:746930 - ABD646

Default Structure
ChEBI IDCHEBI:746930
ChEBI NameABD646
Stars
DefinitionABD646 is a selective, covalent, small-molecule inhibitor of ABHD18, rescues TAFAZZIN (TAZ) mutant phenotypes in fibroblasts from human patients and in fish embryos.
Last Modified13 November 2025
Submitterdoughowe
DownloadsMolfile
FormulaC18H15F3N2O5S
Net Charge0
Average Mass428.388
Monoisotopic Mass428.06538
SMILESCS(=O)(=O)c1ccc(COc2nn(Cc3ccc(C(F)(F)F)cc3)c(=O)o2)cc1
InChIInChI=1S/C18H15F3N2O5S/c1-29(25,26)15-8-4-13(5-9-15)11-27-16-22-23(17(24)28-16)10-12-2-6-14(7-3-12)18(19,20)21/h2-9H,10-11H2,1H3
InChIKeyOYDYQXBJLGIHAN-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
ABD646 (CHEBI:746930) is a organic molecular entity (CHEBI:50860)
Citations