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CHEBI:71644 - lantibiotic
| ChEBI ID | CHEBI:71644 |
| ChEBI Name | lantibiotic |
| Stars | |
| Definition | A class of peptide antibiotic characterised by the presence of the rare thioether amino acids lanthionine or methyllanthionine, as well as the unsaturated amino acids dehydroalanine and 2-aminoisobutyric acid. In contrast to classical peptide antibiotics, lantibiotics are synthesised from precursor genes using the ribosomal pathway and the characteristic rare amino acids are introduced by posttranslational modification procedues into the lantibiotic precursor peptides ('prepeptides'). Lantibiotics are subdivided into two types: type A have long, flexible structures, while type B have rigid, globular structures. |
| Last Modified | 23 August 2013 |
| Submitter | Gareth Owen |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Role: | antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| lantibiotic (CHEBI:71644) is a peptide antibiotic (CHEBI:25903) |
| lantibiotic (CHEBI:71644) is a polypeptide (CHEBI:15841) |
| Incoming Relation(s) |
| type A lantibiotic (CHEBI:71645) is a lantibiotic (CHEBI:71644) |
| type B lantibiotic (CHEBI:71647) is a lantibiotic (CHEBI:71644) |
| Synonym | Source |
|---|---|
| lantibiotics | ChEBI |
| Manual Xrefs | Databases |
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| Lantibiotics | Wikipedia |
| Citations |
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