CHEBI:71416 - phenazopyridine

ChEBI IDCHEBI:71416
ChEBI Namephenazopyridine
Stars
DefinitionA diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
Secondary ChEBI IDCHEBI:8057
Last Modified25 August 2023
DownloadsMolfile
FormulaC11H11N5
Net Charge0
Average Mass213.244
Monoisotopic Mass213.10145
SMILESNc1ccc(N=Nc2ccccc2)c(N)n1
InChIInChI=1S/C11H11N5/c12-10-7-6-9(11(13)14-10)16-15-8-4-2-1-3-5-8/h1-7H,(H4,12,13,14)
InChIKeyQPFYXYFORQJZEC-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
carcinogenic agent  A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
local anaesthetic  Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ChEBI Ontology
Outgoing Relation(s)
phenazopyridine (CHEBI:71416) has role anticoronaviral agent (CHEBI:149553)
phenazopyridine (CHEBI:71416) has role carcinogenic agent (CHEBI:50903)
phenazopyridine (CHEBI:71416) has role local anaesthetic (CHEBI:36333)
phenazopyridine (CHEBI:71416) has role non-narcotic analgesic (CHEBI:35481)
phenazopyridine (CHEBI:71416) is a diaminopyridine (CHEBI:51598)
phenazopyridine (CHEBI:71416) is a monoazo compound (CHEBI:48959)
phenazopyridine (CHEBI:71416) is conjugate base of phenazopyridine(1+) (CHEBI:71420)
Incoming Relation(s)
phenazopyridine(1+) (CHEBI:71420) is conjugate acid of phenazopyridine (CHEBI:71416)
IUPAC Name 
3-(phenyldiazenyl)pyridine-2,6-diamine
INNs  Source
phenazopyridineKEGG DRUG
phenazopyridinumChemIDplus
fenazopiridinaChemIDplus
phénazopyridineWHO MedNet
Synonyms  Source
3-(Phenylazo)-2,6-pyridinediamineKEGG COMPOUND
2,6-Diamino-3-phenylazopyridineChemIDplus
2,6-Diamino-3-(phenylazo)pyridineNIST Chemistry WebBook
Manual XrefsDatabases
C07429KEGG COMPOUND
D08346KEGG DRUG
DB01438DrugBank
WO2010071878Patent
US2009247628Patent
WO2008033466Patent
HMDB0015506HMDB
PhenazopyridineWikipedia
LSM-3705LINCS
Registry NumbersSources
Reaxys:184497Reaxys
CAS:94-78-0KEGG COMPOUND
CAS:94-78-0ChemIDplus
CAS:94-78-0NIST Chemistry WebBook
Citations