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CHEBI:69621 - trichothecin
| Formula | C19H24O5 |
| Net Charge | 0 |
| Average Mass | 332.396 |
| Monoisotopic Mass | 332.16237 |
| SMILES | [H][C@@]12C=C(C)C(=O)C[C@]1(C)[C@@]1(C)[C@H](OC(=O)/C=C\C)C[C@@]([H])(O2)[C@@]12CO2 |
| InChI | InChI=1S/C19H24O5/c1-5-6-16(21)24-14-8-15-19(10-22-19)18(14,4)17(3)9-12(20)11(2)7-13(17)23-15/h5-7,13-15H,8-10H2,1-4H3/b6-5-/t13-,14-,15-,17+,18-,19+/m1/s1 |
| InChIKey | LJWZOKOFCBPNAG-HULHSAFCSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Trichothecium sp. MSX_51320 (ncbitaxon:1094547) | - | PubMed (21978324) | Mycosynthetix fungal strain was isolated by Dr.Barry Katz from leaf litter |
| Trichothecium roseum (ncbitaxon:47278) | |||
| - | PubMed (6993881) | ||
| - | PubMed (21221935) | Strain: LZ93 | |
| Holarrhena floribunda (ncbitaxon:2708850) | stem (BTO:0001300) | PubMed (10650079) | |
| Engleromyces goetzii (ncbitaxon:251718) | - | PubMed (25633363) |
| Roles Classification |
|---|
| Biological Roles: | antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. STAT3 inhibitor An inhibitor of signal transducer and activator of transcription 3 (STAT3) apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. mycotoxin Poisonous substance produced by fungi. mycotoxin Poisonous substance produced by fungi. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| trichothecin (CHEBI:69621) has role antifungal agent (CHEBI:35718) |
| trichothecin (CHEBI:69621) has role antineoplastic agent (CHEBI:35610) |
| trichothecin (CHEBI:69621) has role apoptosis inducer (CHEBI:68495) |
| trichothecin (CHEBI:69621) has role mycotoxin (CHEBI:25442) |
| trichothecin (CHEBI:69621) has role protein synthesis inhibitor (CHEBI:48001) |
| trichothecin (CHEBI:69621) has role STAT3 inhibitor (CHEBI:87183) |
| trichothecin (CHEBI:69621) is a trichothecene (CHEBI:55517) |
| IUPAC Name |
|---|
| 8-oxo-12,13-epoxytrichothec-9-en-4β-yl (2Z)-but-2-enoate |
| Synonyms | Source |
|---|---|
| trichothecin | KEGG COMPOUND |
| (4β)-12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]trichothec-9-en-8-one | ChEBI |
| Citations |
|---|