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CHEBI:69621 - trichothecin
| Formula | C19H24O5 |
| Net Charge | 0 |
| Average Mass | 332.396 |
| Monoisotopic Mass | 332.16237 |
| SMILES | [H][C@@]12C=C(C)C(=O)C[C@]1(C)[C@@]1(C)[C@H](OC(=O)/C=C\C)C[C@@]([H])(O2)[C@@]12CO2 |
| InChI | InChI=1S/C19H24O5/c1-5-6-16(21)24-14-8-15-19(10-22-19)18(14,4)17(3)9-12(20)11(2)7-13(17)23-15/h5-7,13-15H,8-10H2,1-4H3/b6-5-/t13-,14-,15-,17+,18-,19+/m1/s1 |
| InChIKey | LJWZOKOFCBPNAG-HULHSAFCSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Engleromyces goetzii (ncbitaxon:251718) | - | PubMed (25633363) | |
| Holarrhena floribunda (ncbitaxon:2708850) | stem (BTO:0001300) | PubMed (10650079) | |
| Trichothecium roseum (ncbitaxon:47278) | |||
| - | PubMed (6993881) | ||
| - | PubMed (21221935) | Strain: LZ93 | |
| Trichothecium sp. MSX_51320 (ncbitaxon:1094547) | - | PubMed (21978324) | Mycosynthetix fungal strain was isolated by Dr.Barry Katz from leaf litter |
| Roles Classification |
|---|
| Biological Roles: | apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. mycotoxin Poisonous substance produced by fungi. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. STAT3 inhibitor An inhibitor of signal transducer and activator of transcription 3 (STAT3) protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. mycotoxin Poisonous substance produced by fungi. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| trichothecin (CHEBI:69621) has role antifungal agent (CHEBI:35718) |
| trichothecin (CHEBI:69621) has role antineoplastic agent (CHEBI:35610) |
| trichothecin (CHEBI:69621) has role apoptosis inducer (CHEBI:68495) |
| trichothecin (CHEBI:69621) has role mycotoxin (CHEBI:25442) |
| trichothecin (CHEBI:69621) has role protein synthesis inhibitor (CHEBI:48001) |
| trichothecin (CHEBI:69621) has role STAT3 inhibitor (CHEBI:87183) |
| trichothecin (CHEBI:69621) is a trichothecene (CHEBI:55517) |
| IUPAC Name |
|---|
| 8-oxo-12,13-epoxytrichothec-9-en-4β-yl (2Z)-but-2-enoate |
| Synonyms | Source |
|---|---|
| (4β)-12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]trichothec-9-en-8-one | ChEBI |
| trichothecin | KEGG COMPOUND |
| Citations |
|---|