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CHEBI:6950 - mirtazapine
| Formula | C17H19N3 |
| Net Charge | 0 |
| Average Mass | 265.360 |
| Monoisotopic Mass | 265.15790 |
| SMILES | CN1CCN2c3ncccc3Cc3ccccc3C2C1 |
| InChI | InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 |
| InChIKey | RONZAEMNMFQXRA-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. anti-obesity agent Any substance which is used to reduce or control weight. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. histamine antagonist Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. |
| Applications: | H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. oneirogen Any substance that produces or enhances dream-like states of consciousness. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. appetite enhancer A drug which increases appetite. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. histamine antagonist Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mirtazapine (CHEBI:6950) has role anti-obesity agent (CHEBI:74518) |
| mirtazapine (CHEBI:6950) has role antidepressant (CHEBI:35469) |
| mirtazapine (CHEBI:6950) has role antiemetic (CHEBI:50919) |
| mirtazapine (CHEBI:6950) has role antineoplastic agent (CHEBI:35610) |
| mirtazapine (CHEBI:6950) has role antipsychotic agent (CHEBI:35476) |
| mirtazapine (CHEBI:6950) has role anxiolytic drug (CHEBI:35474) |
| mirtazapine (CHEBI:6950) has role appetite enhancer (CHEBI:50779) |
| mirtazapine (CHEBI:6950) has role H1-receptor antagonist (CHEBI:37955) |
| mirtazapine (CHEBI:6950) has role histamine antagonist (CHEBI:37956) |
| mirtazapine (CHEBI:6950) has role oneirogen (CHEBI:146270) |
| mirtazapine (CHEBI:6950) has role serotonergic antagonist (CHEBI:48279) |
| mirtazapine (CHEBI:6950) has role α-adrenergic antagonist (CHEBI:37890) |
| mirtazapine (CHEBI:6950) is a benzazepine (CHEBI:35676) |
| mirtazapine (CHEBI:6950) is a tetracyclic antidepressant (CHEBI:50940) |
| IUPAC Name |
|---|
| 2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| INNs | Source |
|---|---|
| mirtazapina | ChEBI |
| mirtazapine | ChEBI |
| mirtazapinum | ChEBI |
| Synonyms | Source |
|---|---|
| 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine | ChemIDplus |
| 6-azamianserin | ChEMBL |
| Avanza | ChEMBL |
| Mirataz | ChEMBL |
| Mirtazapin | ChEMBL |
| Mirtazapine | KEGG COMPOUND |
| Brand Names | Source |
|---|---|
| Remeron | ChEMBL |
| Remeron soltab | ChEMBL |
| Zispin | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:549345 | Beilstein |
| CAS:61337-67-5 | ChemIDplus |
| Citations |
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