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CHEBI:6924 - miconazole nitrate
| ChEBI ID | CHEBI:6924 |
| ChEBI Name | miconazole nitrate |
| Stars | |
| Definition | A racemate composed of equimolar amounts of (R)- and (S)-miconazole nitrate. An antifungal used for the treatment of athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. |
| Last Modified | 22 July 2015 |
| Formula | C18H15Cl4N3O4 |
| Net Charge | 0 |
| Average Mass | 479.141 |
| Monoisotopic Mass | 476.98167 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | glucocorticoid receptor antagonist An antagonist that binds to and deactivates glucocorticoid receptors. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| miconazole nitrate (CHEBI:6924) has part (R)-miconazole nitrate (CHEBI:82886) |
| miconazole nitrate (CHEBI:6924) has part (S)-miconazole nitrate (CHEBI:82888) |
| miconazole nitrate (CHEBI:6924) has part miconazole (CHEBI:6923) |
| miconazole nitrate (CHEBI:6924) has role antifungal agent (CHEBI:35718) |
| miconazole nitrate (CHEBI:6924) has role antineoplastic agent (CHEBI:35610) |
| miconazole nitrate (CHEBI:6924) has role ergosterol biosynthesis inhibitor (CHEBI:75282) |
| miconazole nitrate (CHEBI:6924) has role glucocorticoid receptor antagonist (CHEBI:82891) |
| miconazole nitrate (CHEBI:6924) is a conazole antifungal drug (CHEBI:87071) |
| miconazole nitrate (CHEBI:6924) is a imidazole antifungal drug (CHEBI:87069) |
| miconazole nitrate (CHEBI:6924) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate |
| Synonyms | Source |
|---|---|
| (±)-miconazole nitrate | ChEBI |
| rac-miconazole nitrate | ChEBI |
| (RS)-miconazole nitrate | ChEBI |
| 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole mononitrate | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| C08070 | KEGG COMPOUND |
| D00882 | KEGG DRUG |
| DB01110 | DrugBank |
| Miconazole | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:4225531 | Reaxys |
| CAS:22832-87-7 | KEGG COMPOUND |
| CAS:22832-87-7 | ChemIDplus |
| Citations |
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