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CHEBI:6904 - metoprolol

Default Structure
ChEBI IDCHEBI:6904
ChEBI Namemetoprolol
Stars
DefinitionA propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Last Modified26 October 2021
DownloadsMolfile
FormulaC15H25NO3
Net Charge0
Average Mass267.369
Monoisotopic Mass267.18344
SMILESCOCCc1ccc(OCC(O)CNC(C)C)cc1
InChIInChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3
InChIKeyIUBSYMUCCVWXPE-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
anti-obesity agent  Any substance which is used to reduce or control weight.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antipsoriatic  A drug used to treat psoriasis.
hypoglycemic agent  A drug which lowers the blood glucose level.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
dermatologic drug  A drug used to treat or prevent skin disorders or for the routine care of skin.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antiatherosclerotic agent  A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
ChEBI Ontology
Outgoing Relation(s)
metoprolol (CHEBI:6904) has role anti-arrhythmia drug (CHEBI:38070)
metoprolol (CHEBI:6904) has role anti-HIV agent (CHEBI:64946)
metoprolol (CHEBI:6904) has role anti-obesity agent (CHEBI:74518)
metoprolol (CHEBI:6904) has role antiatherosclerotic agent (CHEBI:145947)
metoprolol (CHEBI:6904) has role antihypertensive agent (CHEBI:35674)
metoprolol (CHEBI:6904) has role antineoplastic agent (CHEBI:35610)
metoprolol (CHEBI:6904) has role antipsoriatic (CHEBI:50748)
metoprolol (CHEBI:6904) has role cardiovascular drug (CHEBI:35554)
metoprolol (CHEBI:6904) has role dermatologic drug (CHEBI:50177)
metoprolol (CHEBI:6904) has role environmental contaminant (CHEBI:78298)
metoprolol (CHEBI:6904) has role geroprotector (CHEBI:176497)
metoprolol (CHEBI:6904) has role hypoglycemic agent (CHEBI:35526)
metoprolol (CHEBI:6904) has role xenobiotic (CHEBI:35703)
metoprolol (CHEBI:6904) has role β-adrenergic antagonist (CHEBI:35530)
metoprolol (CHEBI:6904) is a aromatic ether (CHEBI:35618)
metoprolol (CHEBI:6904) is a propanolamine (CHEBI:35533)
metoprolol (CHEBI:6904) is a secondary alcohol (CHEBI:35681)
metoprolol (CHEBI:6904) is a secondary amino compound (CHEBI:50995)
IUPAC Name 
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Synonyms  Source
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-olChEBI
CGP-2175ChEMBL
H-93/26ChEMBL
LopressidoneChEMBL
MetoprololKEGG COMPOUND
MetoprololKEGG DRUG
Manual XrefsDatabases
1786DrugCentral
C07202KEGG COMPOUND
D02358KEGG DRUG
DB00264DrugBank
HMDB0001932HMDB
LSM-1259LINCS
MetoprololWikipedia
Registry NumbersSources
Reaxys:1117585Reaxys
CAS:37350-58-6KEGG COMPOUND
CAS:37350-58-6ChemIDplus
CAS:51384-51-1ChemIDplus
CAS:51384-51-1KEGG COMPOUND
Citations