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CHEBI:68847 - azilsartan kamedoxomil

Default Structure
ChEBI IDCHEBI:68847
ChEBI Nameazilsartan kamedoxomil
Stars
DefinitionAn organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension.
Last Modified15 November 2012
SubmitterSteve
DownloadsMolfile
FormulaC30H23N4O8.K
Net Charge0
Average Mass606.632
Monoisotopic Mass606.11530
SMILESCCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2-c2noc(=O)[n-]2)cc1.[K+]
InChIInChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1
InChIKeyIHWFKDWIUSZLCJ-UHFFFAOYSA-M
Roles Classification
Biological Role:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
azilsartan kamedoxomil (CHEBI:68847) has part azilsartan medoxomil(1−) (CHEBI:68849)
azilsartan kamedoxomil (CHEBI:68847) has role angiotensin receptor antagonist (CHEBI:61016)
azilsartan kamedoxomil (CHEBI:68847) has role antihypertensive agent (CHEBI:35674)
azilsartan kamedoxomil (CHEBI:68847) has role prodrug (CHEBI:50266)
azilsartan kamedoxomil (CHEBI:68847) is a organic potassium salt (CHEBI:50394)
IUPAC Name 
potassium 3-{4'-[(2-ethoxy-7-{[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl}-1H-benzimidazol-1-yl)methyl]biphenyl-2-yl}-5-oxo-1,2,4-oxadiazol-4-ide
Synonym  Source
TAK-491ChemIDplus
Brand Name  Source
EdarbiKEGG DRUG
Manual XrefsDatabases
D08865KEGG DRUG
US2005187269Patent
WO2012107814Patent
Registry NumbersSources
Reaxys:12331024Reaxys
CAS:863031-24-7KEGG DRUG