EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:68847 - azilsartan kamedoxomil

ChEBI IDCHEBI:68847
ChEBI Nameazilsartan kamedoxomil
Stars
DefinitionAn organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension.
Last Modified15 November 2012
SubmitterSteve
DownloadsMolfile
FormulaC30H23N4O8.K
Net Charge0
Average Mass606.632
Monoisotopic Mass606.11530
SMILESCCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2-c2noc(=O)[n-]2)cc1.[K+]
InChIInChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1
InChIKeyIHWFKDWIUSZLCJ-UHFFFAOYSA-M
Roles Classification
Biological Role:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
Applications:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
azilsartan kamedoxomil (CHEBI:68847) has part azilsartan medoxomil(1−) (CHEBI:68849)
azilsartan kamedoxomil (CHEBI:68847) has role angiotensin receptor antagonist (CHEBI:61016)
azilsartan kamedoxomil (CHEBI:68847) has role antihypertensive agent (CHEBI:35674)
azilsartan kamedoxomil (CHEBI:68847) has role prodrug (CHEBI:50266)
azilsartan kamedoxomil (CHEBI:68847) is a organic potassium salt (CHEBI:50394)
IUPAC Name 
potassium 3-{4'-[(2-ethoxy-7-{[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl}-1H-benzimidazol-1-yl)methyl]biphenyl-2-yl}-5-oxo-1,2,4-oxadiazol-4-ide
Synonym  Source
TAK-491ChemIDplus
Brand Name  Source
EdarbiKEGG DRUG
Manual XrefsDatabases
D08865KEGG DRUG
WO2012107814Patent
US2005187269Patent
Registry NumbersSources
Reaxys:12331024Reaxys
CAS:863031-24-7KEGG DRUG