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CHEBI:68554 - deferiprone

Default Structure
ChEBI IDCHEBI:68554
ChEBI Namedeferiprone
Stars
DefinitionA member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC7H9NO2
Net Charge0
Average Mass139.154
Monoisotopic Mass139.06333
SMILESCc1c(O)c(=O)ccn1C
InChIInChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
InChIKeyTZXKOCQBRNJULO-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Biological Role:
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
Applications:
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
protective agent  Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
ChEBI Ontology
Outgoing Relation(s)
deferiprone (CHEBI:68554) has role anti-anaemic agent (CHEBI:75835)
deferiprone (CHEBI:68554) has role anti-HIV agent (CHEBI:64946)
deferiprone (CHEBI:68554) has role antiparkinson drug (CHEBI:48407)
deferiprone (CHEBI:68554) has role cardiovascular drug (CHEBI:35554)
deferiprone (CHEBI:68554) has role iron chelator (CHEBI:38157)
deferiprone (CHEBI:68554) has role protective agent (CHEBI:50267)
deferiprone (CHEBI:68554) has role renoprotective agent (CHEBI:231911)
deferiprone (CHEBI:68554) is a 4-pyridones (CHEBI:20485)
IUPAC Name 
3-hydroxy-1,2-dimethylpyridin-4(1H)-one
INNs  Source
deferipronaWHO MedNet
deferiproneChemIDplus
Synonyms  Source
1,2-Dimethyl-3-hydroxypyrid-4-oneChemIDplus
3-Hydroxy-1,2-dimethyl-4(1H)-pyridoneChemIDplus
APO-066ChEMBL
APO-66ChEMBL
CP-20ChEMBL
CP20ChEMBL
Brand Names  Source
Deferiprone lipomedChEMBL
FerriproxKEGG DRUG
Manual XrefsDatabases
4188DrugCentral
D07416KEGG DRUG
DeferiproneWikipedia
LSM-36972LINCS
Registry NumbersSources
Reaxys:1447108Reaxys
CAS:30652-11-0ChemIDplus
CAS:30652-11-0KEGG DRUG
Citations