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CHEBI:6839 - methoxamine

ChEBI IDCHEBI:6839
ChEBI Namemethoxamine
Stars
DefinitionAn amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at α-adrenoceptors with selectivity for the α-1 adrenoceptor subtype similar to phenylephrine .
Last Modified15 March 2018
DownloadsMolfile
FormulaC11H17NO3
Net Charge0
Average Mass211.261
Monoisotopic Mass211.12084
SMILESCOc1ccc(OC)c(C(O)C(C)N)c1
InChIInChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3
InChIKeyWJAJPNHVVFWKKL-UHFFFAOYSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
Applications:
antihypotensive agent  A cardiovascular drug that tends to raise reduced blood pressure.
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
methoxamine (CHEBI:6839) has role antihypotensive agent (CHEBI:137431)
methoxamine (CHEBI:6839) has role α-adrenergic agonist (CHEBI:35569)
methoxamine (CHEBI:6839) is a amphetamines (CHEBI:35338)
Synonyms  Source
MethoxamineKEGG COMPOUND
methoxaminDrugCentral
methoxamedrineChEBI
Manual XrefsDatabases
C07513KEGG COMPOUND
D08201KEGG DRUG
LSM-4423LINCS
Registry NumbersSources
CAS:390-28-3KEGG COMPOUND
CAS:390-28-3ChemIDplus
Citations