CHEBI:6839 - methoxamine

ChEBI IDCHEBI:6839
ChEBI Namemethoxamine
Stars
DefinitionAn amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at α-adrenoceptors with selectivity for the α-1 adrenoceptor subtype similar to phenylephrine .
Last Modified15 March 2018
DownloadsMolfile
FormulaC11H17NO3
Net Charge0
Average Mass211.261
Monoisotopic Mass211.12084
SMILESCOc1ccc(OC)c(C(O)C(C)N)c1
InChIInChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3
InChIKeyWJAJPNHVVFWKKL-UHFFFAOYSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
Applications:
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
antihypotensive agent  A cardiovascular drug that tends to raise reduced blood pressure.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
methoxamine (CHEBI:6839) has role antihypotensive agent (CHEBI:137431)
methoxamine (CHEBI:6839) has role cardiovascular drug (CHEBI:35554)
methoxamine (CHEBI:6839) has role α-adrenergic agonist (CHEBI:35569)
methoxamine (CHEBI:6839) is a amphetamines (CHEBI:35338)
INN  Source
metoxaminaWHO MedNet
Synonyms  Source
methoxamedrineChEBI
methoxaminDrugCentral
MethoxamineKEGG COMPOUND
NRL-001ChEMBL
NRL001ChEMBL
Manual XrefsDatabases
C07513KEGG COMPOUND
D08201KEGG DRUG
LSM-4423LINCS
Registry NumbersSources
CAS:390-28-3ChemIDplus
CAS:390-28-3KEGG COMPOUND
Citations