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CHEBI:6838 - methotrimeprazine
| Formula | C19H24N2OS |
| Net Charge | 0 |
| Average Mass | 328.481 |
| Monoisotopic Mass | 328.16093 |
| SMILES | COc1ccc2c(c1)N(C[C@H](C)CN(C)C)c1ccccc1S2 |
| InChI | InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1 |
| InChIKey | VRQVVMDWGGWHTJ-CQSZACIVSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| methotrimeprazine (CHEBI:6838) has parent hydride 10H-phenothiazine (CHEBI:37931) |
| methotrimeprazine (CHEBI:6838) has role anticoronaviral agent (CHEBI:149553) |
| methotrimeprazine (CHEBI:6838) has role antidepressant (CHEBI:35469) |
| methotrimeprazine (CHEBI:6838) has role antipsychotic agent (CHEBI:35476) |
| methotrimeprazine (CHEBI:6838) has role anxiolytic drug (CHEBI:35474) |
| methotrimeprazine (CHEBI:6838) has role cholinergic antagonist (CHEBI:48873) |
| methotrimeprazine (CHEBI:6838) has role dopaminergic antagonist (CHEBI:48561) |
| methotrimeprazine (CHEBI:6838) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) |
| methotrimeprazine (CHEBI:6838) has role non-narcotic analgesic (CHEBI:35481) |
| methotrimeprazine (CHEBI:6838) has role phenothiazine antipsychotic drug (CHEBI:37930) |
| methotrimeprazine (CHEBI:6838) has role serotonergic antagonist (CHEBI:48279) |
| methotrimeprazine (CHEBI:6838) is a phenothiazines (CHEBI:38093) |
| methotrimeprazine (CHEBI:6838) is a tertiary amine (CHEBI:32876) |
| IUPAC Name |
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| (2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine |
| INNs | Source |
|---|---|
| levomepromazina | ChEBI |
| levomepromazine | WHO MedNet |
| lévomépromazine | ChEBI |
| levomepromazinum | ChEBI |
| Synonyms | Source |
|---|---|
| (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine | ChemIDplus |
| (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine | ChemIDplus |
| 2-Methoxytrimeprazine | ChemIDplus |
| CL 36467 | ChEMBL |
| CL-36467 | ChEMBL |
| CL 39743 | ChEMBL |
| Citations |
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