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CHEBI:68293 - nagilactone F

ChEBI IDCHEBI:68293
ChEBI Namenagilactone F
Stars
DefinitionA diterpene lactone isolated from Podocarpus latifolius and has been shown to exhibit inhibitory activity against activator protein 1 (AP-1).
Last Modified21 August 2013
DownloadsMolfile
FormulaC19H24O4
Net Charge0
Average Mass316.397
Monoisotopic Mass316.16746
SMILES[H][C@@]12[C@@]3([H])C=C4C(=CC(=O)O[C@@H]4C(C)C)[C@@]1(C)CCC[C@]2(C)C(=O)O3
InChIInChI=1S/C19H24O4/c1-10(2)15-11-8-13-16-18(3,12(11)9-14(20)23-15)6-5-7-19(16,4)17(21)22-13/h8-10,13,15-16H,5-7H2,1-4H3/t13-,15-,16-,18-,19+/m1/s1
InChIKeyDYJDPNXKUMPXEJ-DZLVSBGCSA-N
Species of MetaboliteComponentSourceComments
Podocarpus latifolius (ncbitaxon:120620) root (BTO:0001188) PubMed (21306129) Previous component: root bark; CH2Cl2-MeOH(1:1) extract of dried, ground root bark
Roles Classification
Biological Roles:
AP-1 antagonist  An antogonist that interferes with the action of activator protein 1 (AP-1).
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
ChEBI Ontology
Outgoing Relation(s)
nagilactone F (CHEBI:68293) has role AP-1 antagonist (CHEBI:67199)
nagilactone F (CHEBI:68293) has role metabolite (CHEBI:25212)
nagilactone F (CHEBI:68293) is a diterpene lactone (CHEBI:49193)
nagilactone F (CHEBI:68293) is a organic heterotetracyclic compound (CHEBI:38163)
nagilactone F (CHEBI:68293) is a γ-lactone (CHEBI:37581)
nagilactone F (CHEBI:68293) is a δ-lactone (CHEBI:18946)
IUPAC Name 
(3aS,5aR,7R,10bS,10cR)-3a,10b-dimethyl-7-(propan-2-yl)-1,2,3,3a,5a,7,10b,10c-octahydro-4H,9H-[2]benzofuro[7,1-fg]isochromene-4,9-dione
Registry NumbersSources
Reaxys:1399292Reaxys
CAS:36912-00-2ChemIDplus
Citations