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CHEBI:6821 - methaqualone

ChEBI IDCHEBI:6821
ChEBI Namemethaqualone
Stars
DefinitionA member of the class of quinazolines that is quinazolin-4-one substituted at positions 2 and 3 by methyl and o-tolyl groups respectively. A depressant that increases the activity of the GABA receptors in the brain and nervous system, it is used as a sedative and hypnotic medication. It became popular as a recreational drug and club drug in the late 1960s and 1970s.
Last Modified19 June 2017
DownloadsMolfile
FormulaC16H14N2O
Net Charge0
Average Mass250.301
Monoisotopic Mass250.11061
SMILESCc1ccccc1-n1c(C)nc2ccccc2c1=O
InChIInChI=1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3
InChIKeyJEYCTXHKTXCGPB-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA agonist  A drug that binds to and activates γ-aminobutyric acid receptors.
Applications:
GABA agonist  A drug that binds to and activates γ-aminobutyric acid receptors.
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
ChEBI Ontology
Outgoing Relation(s)
methaqualone (CHEBI:6821) has role GABA agonist (CHEBI:51373)
methaqualone (CHEBI:6821) has role sedative (CHEBI:35717)
methaqualone (CHEBI:6821) is a quinazolines (CHEBI:38530)
IUPAC Name 
2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one
INNs  Source
methaqualoneChemIDplus
metacualonaChemIDplus
methaqualonumChemIDplus
Registry NumbersSources
CAS:72-44-6ChemIDplus
Citations