CHEBI:6802 - metformin hydrochloride

ChEBI IDCHEBI:6802
ChEBI Namemetformin hydrochloride
Stars
DefinitionA hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride.
Secondary ChEBI IDCHEBI:90684
Last Modified8 January 2016
SubmitterSteve
DownloadsMolfile
FormulaC4H11N5.HCl
Net Charge0
Average Mass165.628
Monoisotopic Mass165.07812
SMILESCN(C)C(=N)NC(=N)N.Cl
InChIInChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChIKeyOETHQSJEHLVLGH-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Roles:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
anti-obesity agent  Any substance which is used to reduce or control weight.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Applications:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
hypoglycemic agent  A drug which lowers the blood glucose level.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
antifibrotic agent  Any agent which acts to reduce fibrosis.
hypoglycemic agent  A drug which lowers the blood glucose level.
ChEBI Ontology
Outgoing Relation(s)
metformin hydrochloride (CHEBI:6802) has part metformin(1+) (CHEBI:90688)
metformin hydrochloride (CHEBI:6802) has role anti-anaemic agent (CHEBI:75835)
metformin hydrochloride (CHEBI:6802) has role anti-inflammatory agent (CHEBI:67079)
metformin hydrochloride (CHEBI:6802) has role anti-obesity agent (CHEBI:74518)
metformin hydrochloride (CHEBI:6802) has role antifibrotic agent (CHEBI:233423)
metformin hydrochloride (CHEBI:6802) has role antineoplastic agent (CHEBI:35610)
metformin hydrochloride (CHEBI:6802) has role cardiovascular drug (CHEBI:35554)
metformin hydrochloride (CHEBI:6802) has role environmental contaminant (CHEBI:78298)
metformin hydrochloride (CHEBI:6802) has role geroprotector (CHEBI:176497)
metformin hydrochloride (CHEBI:6802) has role hypoglycemic agent (CHEBI:35526)
metformin hydrochloride (CHEBI:6802) has role immunosuppressive agent (CHEBI:35705)
metformin hydrochloride (CHEBI:6802) has role xenobiotic (CHEBI:35703)
metformin hydrochloride (CHEBI:6802) is a biguanides (CHEBI:53662)
metformin hydrochloride (CHEBI:6802) is a hydrochloride (CHEBI:36807)
metformin hydrochloride (CHEBI:6802) is a organic molecular entity (CHEBI:50860)
Incoming Relation(s)
Synjardy (CHEBI:90875) has part metformin hydrochloride (CHEBI:6802)
IUPAC Name 
N,N-dimethylimidodicarbonimidic diamide hydrochloride
Synonyms  Source
1,1-Dimethylbiguanide hydrochlorideChemIDplus
1,1-Dimethylbiguanide monohydrochlorideChemIDplus
ApophageChEMBL
BenofominChEMBL
Dimethylbiguanide hydrochlorideChemIDplus
EX-404ChEMBL
Brand Names  Source
Bolamyn srChEMBL
Diagemet xlChEMBL
Glucamet 500ChEMBL
Glucamet 850ChEMBL
Glucient srChEMBL
GlucophageKEGG DRUG
Manual XrefsDatabases
D00944KEGG DRUG
DB00331DrugBank
MetforminWikipedia
Registry NumbersSources
Reaxys:3626131Reaxys
CAS:1115-70-4KEGG DRUG
CAS:1115-70-4ChemIDplus
Citations