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CHEBI:6801 - metformin
| Formula | C4H11N5 |
| Net Charge | 0 |
| Average Mass | 129.167 |
| Monoisotopic Mass | 129.10145 |
| SMILES | CN(C)C(=N)NC(=N)N |
| InChI | InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8) |
| InChIKey | XZWYZXLIPXDOLR-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
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| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antiviral agent A substance that destroys or inhibits replication of viruses. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. anti-obesity agent Any substance which is used to reduce or control weight. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). antipsoriatic A drug used to treat psoriasis. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. anticonvulsant A drug used to prevent seizures or reduce their severity. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. hypoglycemic agent A drug which lowers the blood glucose level. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antirheumatic drug A drug used to treat rheumatoid arthritis. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. anti-inflammatory agent Any compound that has anti-inflammatory effects. antiparkinson drug A drug used in the treatment of Parkinson's disease. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| metformin (CHEBI:6801) has functional parent biguanide (CHEBI:3095) |
| metformin (CHEBI:6801) has role analgesic (CHEBI:35480) |
| metformin (CHEBI:6801) has role anti-anaemic agent (CHEBI:75835) |
| metformin (CHEBI:6801) has role anti-arrhythmia drug (CHEBI:38070) |
| metformin (CHEBI:6801) has role anti-HIV agent (CHEBI:64946) |
| metformin (CHEBI:6801) has role anti-inflammatory agent (CHEBI:67079) |
| metformin (CHEBI:6801) has role anti-obesity agent (CHEBI:74518) |
| metformin (CHEBI:6801) has role antiatherosclerotic agent (CHEBI:145947) |
| metformin (CHEBI:6801) has role antibacterial agent (CHEBI:33282) |
| metformin (CHEBI:6801) has role anticonvulsant (CHEBI:35623) |
| metformin (CHEBI:6801) has role anticoronaviral agent (CHEBI:149553) |
| metformin (CHEBI:6801) has role antidepressant (CHEBI:35469) |
| metformin (CHEBI:6801) has role antiglaucoma drug (CHEBI:39456) |
| metformin (CHEBI:6801) has role antihypertensive agent (CHEBI:35674) |
| metformin (CHEBI:6801) has role antimalarial (CHEBI:38068) |
| metformin (CHEBI:6801) has role antineoplastic agent (CHEBI:35610) |
| metformin (CHEBI:6801) has role antiparkinson drug (CHEBI:48407) |
| metformin (CHEBI:6801) has role antipsoriatic (CHEBI:50748) |
| metformin (CHEBI:6801) has role antipsychotic agent (CHEBI:35476) |
| metformin (CHEBI:6801) has role antirheumatic drug (CHEBI:35842) |
| metformin (CHEBI:6801) has role antitubercular agent (CHEBI:33231) |
| metformin (CHEBI:6801) has role antiviral agent (CHEBI:22587) |
| metformin (CHEBI:6801) has role anxiolytic drug (CHEBI:35474) |
| metformin (CHEBI:6801) has role cardiovascular drug (CHEBI:35554) |
| metformin (CHEBI:6801) has role environmental contaminant (CHEBI:78298) |
| metformin (CHEBI:6801) has role geroprotector (CHEBI:176497) |
| metformin (CHEBI:6801) has role hypoglycemic agent (CHEBI:35526) |
| metformin (CHEBI:6801) has role immunosuppressive agent (CHEBI:35705) |
| metformin (CHEBI:6801) has role insulin-sensitizing drug (CHEBI:50864) |
| metformin (CHEBI:6801) has role leprostatic drug (CHEBI:35816) |
| metformin (CHEBI:6801) has role xenobiotic (CHEBI:35703) |
| metformin (CHEBI:6801) is a guanidines (CHEBI:24436) |
| metformin (CHEBI:6801) is conjugate base of metformin(1+) (CHEBI:90688) |
| Incoming Relation(s) |
| metformin(1+) (CHEBI:90688) is conjugate acid of metformin (CHEBI:6801) |
| IUPAC Name |
|---|
| N,N-dimethyltriimidodicarbonic diamide |
| INNs | Source |
|---|---|
| metformin | WHO MedNet |
| metformina | WHO MedNet |
| metformine | WHO MedNet |
| metforminum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1,1-dimethylbiguanide | ChemIDplus |
| dimethylbiguanide | ChemIDplus |
| dimethyldiguanide | ChemIDplus |
| N,N-dimethylbiguanide | ChemIDplus |
| N,N-dimethyldiguanide | ChemIDplus |
| N,N-dimethylguanylguanidine | DrugCentral |
| Citations |
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