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CHEBI:67272 - perifosine

ChEBI IDCHEBI:67272
ChEBI Nameperifosine
Stars
DefinitionA phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group.
Last Modified25 September 2012
Submittermwilliams
DownloadsMolfile
FormulaC25H52NO4P
Net Charge0
Average Mass461.668
Monoisotopic Mass461.36340
SMILESCCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](C)(C)CC1
InChIInChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3
InChIKeySZFPYBIJACMNJV-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor  An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
ChEBI Ontology
Outgoing Relation(s)
perifosine (CHEBI:67272) has functional parent octadecan-1-ol (CHEBI:32154)
perifosine (CHEBI:67272) has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor (CHEBI:50914)
perifosine (CHEBI:67272) is a ammonium betaine (CHEBI:35284)
perifosine (CHEBI:67272) is a phospholipid (CHEBI:16247)
IUPAC Name 
1,1-dimethylpiperidinium-4-yl octadecyl phosphate
Synonym  Source
KRX-0401ChemIDplus
Manual XrefsDatabases
PerifosineWikipedia
Registry NumbersSources
Reaxys:11186113Reaxys
CAS:157716-52-4ChemIDplus
Citations