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CHEBI:6717 - mefenamic acid
| Formula | C15H15NO2 |
| Net Charge | 0 |
| Average Mass | 241.290 |
| Monoisotopic Mass | 241.11028 |
| SMILES | Cc1cccc(Nc2ccccc2C(=O)O)c1C |
| InChI | InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18) |
| InChIKey | HYYBABOKPJLUIN-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antirheumatic drug A drug used to treat rheumatoid arthritis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mefenamic acid (CHEBI:6717) has role analgesic (CHEBI:35480) |
| mefenamic acid (CHEBI:6717) has role antipyretic (CHEBI:35493) |
| mefenamic acid (CHEBI:6717) has role antirheumatic drug (CHEBI:35842) |
| mefenamic acid (CHEBI:6717) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| mefenamic acid (CHEBI:6717) has role environmental contaminant (CHEBI:78298) |
| mefenamic acid (CHEBI:6717) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| mefenamic acid (CHEBI:6717) has role xenobiotic (CHEBI:35703) |
| mefenamic acid (CHEBI:6717) is a aminobenzoic acid (CHEBI:22495) |
| mefenamic acid (CHEBI:6717) is a secondary amino compound (CHEBI:50995) |
| IUPAC Name |
|---|
| 2-[(2,3-dimethylphenyl)amino]benzoic acid |
| INNs | Source |
|---|---|
| ácido mefenámico | WHO MedNet |
| acidum mefenamicum | ChemIDplus |
| acide méfénamique | WHO MedNet |
| mefenamic acid | ChemIDplus |
| Synonyms | Source |
|---|---|
| Mefenaminsaeure | ChemIDplus |
| N-(2,3-xylyl)-2-aminobenzoic acid | ChemIDplus |
| N-2,3-xylylanthranilic acid | ChemIDplus |
| INF 3355 | ChemIDplus |
| INF-3355 | ChemIDplus |
| CI-473 | ChemIDplus |
| Brand Name | Source |
|---|---|
| Ponstel | KEGG DRUG |
| Citations |
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