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CHEBI:66880 - florbetapir F-18

ChEBI IDCHEBI:66880
ChEBI Nameflorbetapir F-18
Stars
DefinitionAn aromatic ether consisting of a pyridine ring substituted at position 2 by a 2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy group and at position 5 and a 2-(4-methylaminophenyl)vinyl group. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC20H25N2O3
Net Charge0
Average Mass359.432
Monoisotopic Mass359.18746
SMILESCNc1ccc(/C=C/c2ccc(OCCOCCOCC[18F])nc2)cc1
InChIInChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1
InChIKeyYNDIAUKFXKEXSV-CRYLGTRXSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Applications:
radiopharmaceutical  Any pharmaceutical compound containing a radioisotope.
ChEBI Ontology
Outgoing Relation(s)
florbetapir F-18 (CHEBI:66880) has role radioactive imaging agent (CHEBI:37336)
florbetapir F-18 (CHEBI:66880) is a 18F radiopharmaceutical (CHEBI:49127)
florbetapir F-18 (CHEBI:66880) is a aromatic ether (CHEBI:35618)
florbetapir F-18 (CHEBI:66880) is a organofluorine compound (CHEBI:37143)
florbetapir F-18 (CHEBI:66880) is a pyridines (CHEBI:26421)
florbetapir F-18 (CHEBI:66880) is a substituted aniline (CHEBI:48975)
IUPAC Name 
4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline
Synonym  Source
FlorbetapirChemIDplus
Brand Name  Source
AmyvidKEGG DRUG
Manual XrefsDatabases
D09617KEGG DRUG
4285DrugCentral
Registry NumbersSources
CAS:956103-76-7KEGG DRUG
CAS:956103-76-7ChemIDplus
Citations