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CHEBI:66638 - nothramicin

Default Structure
ChEBI IDCHEBI:66638
ChEBI Namenothramicin
Stars
DefinitionAn anthracycline antibiotic isolated from the culture broth of Nocardia sp. MJ896-43F17. It exhibits significant antimycobacterial activity against several drug-resistant Mycobacterium smegmatis strains.
Last Modified5 March 2020
DownloadsMolfile
FormulaC30H37NO11
Net Charge0
Average Mass587.622
Monoisotopic Mass587.23666
SMILESCOc1ccc(O)c2c1C(=O)c1cc3c(c(O)c1C2=O)C(OC1CC(C)(N(C)C)C(O)C(C)O1)C(OC)C(C)(O)C3O
InChIInChI=1S/C30H37NO11/c1-12-26(36)29(2,31(4)5)11-17(41-12)42-25-19-14(27(37)30(3,38)28(25)40-7)10-13-18(23(19)34)24(35)20-15(32)8-9-16(39-6)21(20)22(13)33/h8-10,12,17,25-28,32,34,36-38H,11H2,1-7H3
InChIKeyXXHMZNPASHQZPM-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Nocardia (ncbitaxon:1821) - PubMed (9544933) Strain: MJ896-43F17
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
antimycobacterial drug  A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antimycobacterial drug  A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
ChEBI Ontology
Outgoing Relation(s)
nothramicin (CHEBI:66638) has role antimycobacterial drug (CHEBI:64912)
nothramicin (CHEBI:66638) is a aminoglycoside (CHEBI:47779)
nothramicin (CHEBI:66638) is a anthracycline antibiotic (CHEBI:49322)
nothramicin (CHEBI:66638) is a aromatic ether (CHEBI:35618)
nothramicin (CHEBI:66638) is a deoxy hexoside (CHEBI:35315)
nothramicin (CHEBI:66638) is a tertiary amino compound (CHEBI:50996)
IUPAC Name 
3,4,10,12-tetrahydroxy-2,7-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-3-methylhexopyranoside
Registry NumbersSources
CAS:205752-47-2ChemIDplus
Citations