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CHEBI:66577 - lindechunine A

ChEBI IDCHEBI:66577
ChEBI Namelindechunine A
Stars
DefinitionAn isoquinoline alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2, methoxy groups at positions 3 and 11 and a hydroxy group at position 10. Isolated from the roots of Lindera chunii, it exhibits anti-HIV activity.
Last Modified22 March 2013
DownloadsMolfile
FormulaC19H13NO6
Net Charge0
Average Mass351.314
Monoisotopic Mass351.07429
SMILESCOc1c(O)ccc2c1-c1c3c(c(OC)c4ccnc(c14)C2=O)OCO3
InChIInChI=1S/C19H13NO6/c1-23-16-9-5-6-20-14-11(9)13(18-19(16)26-7-25-18)12-8(15(14)22)3-4-10(21)17(12)24-2/h3-6,21H,7H2,1-2H3
InChIKeyZLFKJSKABHQLAQ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Lindera chunii (ncbitaxon:344093) root (BTO:0001188) PubMed (12237535)
Roles Classification
Biological Roles:
HIV-1 integrase inhibitor  An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
ChEBI Ontology
Outgoing Relation(s)
lindechunine A (CHEBI:66577) has functional parent aporphine (CHEBI:35643)
lindechunine A (CHEBI:66577) has role HIV-1 integrase inhibitor (CHEBI:67268)
lindechunine A (CHEBI:66577) has role metabolite (CHEBI:25212)
lindechunine A (CHEBI:66577) is a aromatic ether (CHEBI:35618)
lindechunine A (CHEBI:66577) is a cyclic ketone (CHEBI:3992)
lindechunine A (CHEBI:66577) is a isoquinoline alkaloid (CHEBI:24921)
lindechunine A (CHEBI:66577) is a organic heteropentacyclic compound (CHEBI:38164)
lindechunine A (CHEBI:66577) is a oxacycle (CHEBI:38104)
lindechunine A (CHEBI:66577) is a phenols (CHEBI:33853)
IUPAC Name 
11-hydroxy-4,12-dimethoxy-8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-8-one
Registry NumbersSources
Reaxys:9292933Reaxys
Citations