CHEBI:6651 - malathion

ChEBI IDCHEBI:6651
ChEBI Namemalathion
Stars
DefinitionA racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Last Modified23 July 2018
Wikipedia
Roles Classification
Biological Roles:
EC 3.1.1.7 (acetylcholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.8 (cholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
Applications:
pediculicide  Substance used to treat lice (genus Pediculus) infestation.
agrochemical  An agrochemical is a substance that is used in agriculture or horticulture.
proinsecticide  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide.
scabicide  An acaricide that kills mites of the genus Sarcoptes.
antiparasitic agent  A substance used to treat or prevent parasitic infections.
insecticide  Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
pesticide  Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
pesticide  Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
ChEBI Ontology
Outgoing Relation(s)
malathion (CHEBI:6651) has part (R)-malathion (CHEBI:141475)
malathion (CHEBI:6651) has part (S)-malathion (CHEBI:141476)
malathion (CHEBI:6651) has role agrochemical (CHEBI:33286)
malathion (CHEBI:6651) has role antiparasitic agent (CHEBI:35442)
malathion (CHEBI:6651) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462)
malathion (CHEBI:6651) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
malathion (CHEBI:6651) has role pediculicide (CHEBI:38706)
malathion (CHEBI:6651) has role proinsecticide (CHEBI:136644)
malathion (CHEBI:6651) has role scabicide (CHEBI:73333)
malathion (CHEBI:6651) is a organothiophosphate insecticide (CHEBI:25715)
malathion (CHEBI:6651) is a racemate (CHEBI:60911)
IUPAC Name 
rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
Synonyms  Source
8059HCChEMBL
carbophosNIST Chemistry WebBook
diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioateChEBI
diethyl ((dimethoxyphosphinothioyl)thio)butanedioateChEBI
diethyl (dimethoxyphosphinothioylthio)succinateChemIDplus
[(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl esterNIST Chemistry WebBook
Brand Names  Source
CythionChEMBL
Derbac-mChEMBL
OrganodermChEMBL
PriodermChEMBL
Quellada-mChEMBL
Suleo-mChEMBL
Manual XrefsDatabases
1626DrugCentral
C07497KEGG COMPOUND
D00534KEGG DRUG
DB00772DrugBank
MalathionWikipedia
Registry NumbersSources
Reaxys:1804525Reaxys
CAS:121-75-5ChemIDplus
CAS:121-75-5KEGG COMPOUND
CAS:121-75-5NIST Chemistry WebBook
Citations