CHEBI:6651 - malathion

ChEBI IDCHEBI:6651
ChEBI Namemalathion
Stars
DefinitionA racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Last Modified23 July 2018
Wikipedia
Roles Classification
Biological Roles:
EC 3.1.1.8 (cholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
EC 3.1.1.7 (acetylcholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
Applications:
proinsecticide  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide.
agrochemical  An agrochemical is a substance that is used in agriculture or horticulture.
pediculicide  Substance used to treat lice (genus Pediculus) infestation.
scabicide  An acaricide that kills mites of the genus Sarcoptes.
insecticide  Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
pesticide  Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
pesticide  Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
ChEBI Ontology
Outgoing Relation(s)
malathion (CHEBI:6651) has part (R)-malathion (CHEBI:141475)
malathion (CHEBI:6651) has part (S)-malathion (CHEBI:141476)
malathion (CHEBI:6651) has role agrochemical (CHEBI:33286)
malathion (CHEBI:6651) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462)
malathion (CHEBI:6651) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
malathion (CHEBI:6651) has role pediculicide (CHEBI:38706)
malathion (CHEBI:6651) has role proinsecticide (CHEBI:136644)
malathion (CHEBI:6651) has role scabicide (CHEBI:73333)
malathion (CHEBI:6651) is a organothiophosphate insecticide (CHEBI:25715)
malathion (CHEBI:6651) is a racemate (CHEBI:60911)
IUPAC Name 
rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
Synonyms  Source
MalathionKEGG COMPOUND
KarbofosChemIDplus
diethyl (dimethoxyphosphinothioylthio)succinateChemIDplus
O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl)ChemIDplus
O,O-dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphateChemIDplus
O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioateChemIDplus
Manual XrefsDatabases
C07497KEGG COMPOUND
MalathionWikipedia
DB00772DrugBank
D00534KEGG DRUG
1626DrugCentral
Registry NumbersSources
Reaxys:1804525Reaxys
CAS:121-75-5KEGG COMPOUND
CAS:121-75-5ChemIDplus
CAS:121-75-5NIST Chemistry WebBook
Citations