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CHEBI:66404 - moromycin B

ChEBI IDCHEBI:66404
ChEBI Namemoromycin B
Stars
DefinitionAn angucycline that consists of tetrangomycin linked to a deoxy sugar moiety at position 9 via a C-glycosidic bond. It is isolated from Streptomyces sp.KY002 and exhibits cytotoxicity against human lung cancer and MCF-7 human breast cancer cells.
Last Modified22 October 2012
DownloadsMolfile
FormulaC31H30O10
Net Charge0
Average Mass562.571
Monoisotopic Mass562.18390
SMILES[H][C@@]12O[C@@H](C)C(=O)C[C@]1([H])O[C@]1([H])C[C@H](c3ccc4c(c3O)C(=O)c3ccc5c(c3C4=O)C(=O)C[C@](C)(O)C5)O[C@H](C)[C@@]1([H])O2
InChIInChI=1S/C31H30O10/c1-12-18(32)8-22-30(39-12)41-29-13(2)38-20(9-21(29)40-22)15-6-7-17-25(26(15)34)28(36)16-5-4-14-10-31(3,37)11-19(33)23(14)24(16)27(17)35/h4-7,12-13,20-22,29-30,34,37H,8-11H2,1-3H3/t12-,13+,20+,21+,22-,29+,30-,31+/m0/s1
InChIKeyIVVLBSCKLIYBCU-GEMPFEMJSA-N
Species of MetaboliteComponentSourceComments
Streptomyces sp. (ncbitaxon:1931) - PubMed (18666798) Strain: KY002
Roles Classification
Biological Roles:
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
moromycin B (CHEBI:66404) has functional parent tetrangomycin (CHEBI:32211)
moromycin B (CHEBI:66404) has role antimicrobial agent (CHEBI:33281)
moromycin B (CHEBI:66404) has role antineoplastic agent (CHEBI:35610)
moromycin B (CHEBI:66404) is a C-glycosyl compound (CHEBI:20857)
moromycin B (CHEBI:66404) is a angucycline antibiotic (CHEBI:70737)
Registry NumbersSources
Reaxys:19172513Reaxys
Citations