EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:66403 - moromycin A

ChEBI IDCHEBI:66403
ChEBI Namemoromycin A
Stars
DefinitionAn angucycline antibiotic that consists of a tetrangomycin skeleton linked to deoxy sugars through C-glycosidic and O-glycosidic bonds at positions 9 and 3 respectively. It is isolated from Streptomyces sp.KY002 and exhibits cytotoxicity against human lung cancer and MCF-7 human breast cancer cells.
Last Modified22 October 2012
DownloadsMolfile
FormulaC43H46O14
Net Charge0
Average Mass786.827
Monoisotopic Mass786.28876
SMILES[H][C@]1(O[C@H]2CC[C@H](O[C@@]3(C)CC(=O)c4c(ccc5c4C(=O)c4ccc([C@H]6C[C@@]7([H])O[C@@]8([H])CC(=O)[C@H](C)O[C@@]8([H])O[C@]7([H])[C@@H](C)O6)c(O)c4C5=O)C3)O[C@H]2C)C=CC(=O)[C@H](C)O1
InChIInChI=1S/C43H46O14/c1-18-26(44)10-12-33(51-18)55-29-11-13-34(52-20(29)3)57-43(5)16-22-6-7-24-36(35(22)28(46)17-43)39(48)25-9-8-23(38(47)37(25)40(24)49)30-15-31-41(21(4)50-30)56-42-32(54-31)14-27(45)19(2)53-42/h6-10,12,18-21,29-34,41-42,47H,11,13-17H2,1-5H3/t18-,19-,20-,21+,29-,30+,31+,32-,33-,34-,41+,42-,43+/m0/s1
InChIKeyYXQYFVURWVZIMD-CZMJNFCQSA-N
Species of MetaboliteComponentSourceComments
Streptomyces sp. (ncbitaxon:1931) - PubMed (18666798) Strain: KY002
Roles Classification
Biological Roles:
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
moromycin A (CHEBI:66403) has functional parent tetrangomycin (CHEBI:32211)
moromycin A (CHEBI:66403) has role antineoplastic agent (CHEBI:35610)
moromycin A (CHEBI:66403) is a C-glycosyl compound (CHEBI:20857)
moromycin A (CHEBI:66403) is a angucycline antibiotic (CHEBI:70737)
moromycin A (CHEBI:66403) is a glycoside (CHEBI:24400)
Registry NumbersSources
Reaxys:19172515Reaxys
Citations