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CHEBI:66182 - taiwanhomoflavone A

ChEBI IDCHEBI:66182
ChEBI Nametaiwanhomoflavone A
Stars
DefinitionA biflavonoid that is a dimer resulting from the coupling of 7,4'-dimethoxy-5-hydroxy-6-methylflavone and 5,7,4'-trihydroxyflavone resulting in a bond between C-3' of the methoxyphenyl ring and C-8 of the chromene ring respectively. Isolated from Cephalotaxus wilsoniana, it exhibits cytotoxic activity.
Last Modified9 July 2013
DownloadsMolfile
FormulaC33H24O10
Net Charge0
Average Mass580.545
Monoisotopic Mass580.13695
SMILESCOc1ccc(-c2cc(=O)c3c(O)c(C)c(OC)cc3o2)cc1-c1c(O)cc(O)c2c(=O)cc(-c3ccc(O)cc3)oc12
InChIInChI=1S/C33H24O10/c1-15-25(41-3)14-28-31(32(15)39)23(38)13-27(42-28)17-6-9-24(40-2)19(10-17)29-20(35)11-21(36)30-22(37)12-26(43-33(29)30)16-4-7-18(34)8-5-16/h4-14,34-36,39H,1-3H3
InChIKeyBZHVWUXJPKVWAI-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Cephalotaxus wilsoniana (ncbitaxon:50179)
twig (BTO:0001411) PubMed (10726874)
stem (BTO:0001300) PubMed (10726874)
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
taiwanhomoflavone A (CHEBI:66182) has role antineoplastic agent (CHEBI:35610)
taiwanhomoflavone A (CHEBI:66182) has role metabolite (CHEBI:25212)
taiwanhomoflavone A (CHEBI:66182) is a biaryl (CHEBI:64459)
taiwanhomoflavone A (CHEBI:66182) is a biflavonoid (CHEBI:50128)
taiwanhomoflavone A (CHEBI:66182) is a hydroxyflavone (CHEBI:24698)
taiwanhomoflavone A (CHEBI:66182) is a methoxyflavone (CHEBI:25241)
IUPAC Name 
2-{3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-4-methoxyphenyl}-5-hydroxy-7-methoxy-6-methyl-4H-chromen-4-one
Registry NumbersSources
Reaxys:8666542Reaxys
Citations