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CHEBI:66064 - 10-hydroxycanthin-6-one

ChEBI IDCHEBI:66064
ChEBI Name10-hydroxycanthin-6-one
Stars
DefinitionAn indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from Simaba multiflora, it exhibits antineoplastic activity.
Last Modified7 November 2013
DownloadsMolfile
FormulaC14H8N2O2
Net Charge0
Average Mass236.230
Monoisotopic Mass236.05858
SMILESO=c1ccc2nccc3c4cc(O)ccc4n1c23
InChIInChI=1S/C14H8N2O2/c17-8-1-3-12-10(7-8)9-5-6-15-11-2-4-13(18)16(12)14(9)11/h1-7,17H
InChIKeyFZLISVGXWLVEPB-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Simaba multiflora (IPNI:236532-2) xylem (BTO:0001468) PubMed (6875577) Previous component: wood;
Roles Classification
Biological Roles:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
10-hydroxycanthin-6-one (CHEBI:66064) has functional parent canthin-6-one (CHEBI:3363)
10-hydroxycanthin-6-one (CHEBI:66064) has role antineoplastic agent (CHEBI:35610)
10-hydroxycanthin-6-one (CHEBI:66064) has role metabolite (CHEBI:25212)
10-hydroxycanthin-6-one (CHEBI:66064) is a indole alkaloid (CHEBI:38958)
10-hydroxycanthin-6-one (CHEBI:66064) is a organic heterotetracyclic compound (CHEBI:38163)
IUPAC Name 
10-hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
Synonym  Source
ervineChEBI
Manual XrefsDatabases
139791ChemSpider
Registry NumbersSources
Reaxys:5340157Reaxys
CAS:86293-41-6ChemIDplus
Citations