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CHEBI:65964 - gilvusmycin

ChEBI IDCHEBI:65964
ChEBI Namegilvusmycin
Stars
DefinitionAn antibiotic isolated from the culture broth of Streptomyces sp. QM16 with potent cytotoxic activity against the human tumor cells.
Last Modified21 September 2012
DownloadsMolfile
FormulaC38H34N6O8
Net Charge0
Average Mass702.724
Monoisotopic Mass702.24381
SMILESCOc1c(O)c2c(c3cc(C(=O)N4CCc5c4c(O)c(OC)c4nc(C(=O)N6CC7CC78C6=CC(=O)c6ncc(C)c68)cc54)nc13)CCN2C(C)=O
InChIInChI=1S/C38H34N6O8/c1-15-13-39-29-24(46)11-25-38(26(15)29)12-17(38)14-44(25)37(50)23-10-21-19-6-8-43(31(19)33(48)35(52-4)28(21)41-23)36(49)22-9-20-18-5-7-42(16(2)45)30(18)32(47)34(51-3)27(20)40-22/h9-11,13,17,39-41,47-48H,5-8,12,14H2,1-4H3
InChIKeyXUBJLJZOSKJNMY-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Streptomyces sp. (ncbitaxon:1931) - PubMed (10348041) Strain: QM16
Roles Classification
Biological Roles:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
gilvusmycin (CHEBI:65964) has role antimicrobial agent (CHEBI:33281)
gilvusmycin (CHEBI:65964) has role antineoplastic agent (CHEBI:35610)
gilvusmycin (CHEBI:65964) has role metabolite (CHEBI:25212)
gilvusmycin (CHEBI:65964) is a aromatic ether (CHEBI:35618)
gilvusmycin (CHEBI:65964) is a bridged compound (CHEBI:35990)
gilvusmycin (CHEBI:65964) is a cyclic ketone (CHEBI:3992)
gilvusmycin (CHEBI:65964) is a organonitrogen heterocyclic compound (CHEBI:38101)
gilvusmycin (CHEBI:65964) is a phenols (CHEBI:33853)
IUPAC Name 
6-({6-[(6-acetyl-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl)carbonyl]-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl}carbonyl)-3-methyl-4,4a,5,6-tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-8(1H)-one
Registry NumbersSources
Reaxys:8382539Reaxys
Citations