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CHEBI:65886 - euphornin L

ChEBI IDCHEBI:65886
ChEBI Nameeuphornin L
Stars
DefinitionA macrocyclic diterpenoid isolated from Euphorbia helioscopia and has been shown to exhibit cytotoxicity against HL-60 cell lines.
Last Modified25 January 2013
DownloadsMolfile
FormulaC35H46O10
Net Charge0
Average Mass626.743
Monoisotopic Mass626.30910
SMILES[H][C@@]12/C=C(\C)[C@H](OC(C)=O)C[C@@H](OC(C)=O)C(C)(C)/C=C/[C@H](C)[C@@H](OC(C)=O)[C@@]1(OC(C)=O)C[C@@H](C)[C@@H]2OC(=O)c1ccccc1
InChIInChI=1S/C35H46O10/c1-20-15-16-34(8,9)30(42-24(5)37)18-29(41-23(4)36)21(2)17-28-31(44-33(40)27-13-11-10-12-14-27)22(3)19-35(28,45-26(7)39)32(20)43-25(6)38/h10-17,20,22,28-32H,18-19H2,1-9H3/b16-15+,21-17+/t20-,22+,28-,29+,30+,31-,32+,35+/m0/s1
InChIKeyFZKCYZNAORCYGO-YJKPJJMFSA-N
Species of MetaboliteComponentSourceComments
Euphorbia helioscopia (ncbitaxon:154990) whole plant (BTO:0001461) PubMed (19099222)
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
euphornin L (CHEBI:65886) has role antineoplastic agent (CHEBI:35610)
euphornin L (CHEBI:65886) has role metabolite (CHEBI:25212)
euphornin L (CHEBI:65886) is a acetate ester (CHEBI:47622)
euphornin L (CHEBI:65886) is a benzoate ester (CHEBI:36054)
euphornin L (CHEBI:65886) is a diterpenoid (CHEBI:23849)
euphornin L (CHEBI:65886) is a macrocycle (CHEBI:51026)
IUPAC Name 
(1S,2R,3aR,4R,5S,6E,9R,11R,12E,13aS)-3a,4,9,11-tetrakis(acetyloxy)-2,5,8,8,12-pentamethyl-2,3,3a,4,5,8,9,10,11,13a-decahydro-1H-cyclopenta[12]annulen-1-yl benzoate
Citations