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CHEBI:65849 - epichlicin

ChEBI IDCHEBI:65849
ChEBI Nameepichlicin
Stars
DefinitionA homodetic cyclic peptide containing L-Pro, D-Tyr, L-Ser, L-Asn and L-Gln as the amino acid residues. Isolated from an endophytic fungus, Epichloe typhina, it exhibits inhibitory activity toward the spore germination of Cladosporium phlei, a pathogenic fungus of the timothy plant.
Last Modified6 July 2015
DownloadsMolfile
FormulaC48H74N12O14
Net Charge0
Average Mass1043.190
Monoisotopic Mass1042.54475
SMILESCCCCCCCCCCC[C@@H]1CC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N2CCC[C@H]2C(=O)N1
InChIInChI=1S/C48H74N12O14/c1-2-3-4-5-6-7-8-9-10-12-28-22-41(67)54-32(23-38(50)64)44(70)56-31(21-27-14-16-29(62)17-15-27)43(69)57-33(24-39(51)65)45(71)55-30(18-19-37(49)63)42(68)59-35(26-61)46(72)58-34(25-40(52)66)48(74)60-20-11-13-36(60)47(73)53-28/h14-17,28,30-36,61-62H,2-13,18-26H2,1H3,(H2,49,63)(H2,50,64)(H2,51,65)(H2,52,66)(H,53,73)(H,54,67)(H,55,71)(H,56,70)(H,57,69)(H,58,72)(H,59,68)/t28-,30+,31-,32+,33+,34+,35+,36+/m1/s1
InChIKeyQPLUQODTAQYAFC-FVBCJJOCSA-N
Species of MetaboliteComponentSourceComments
Epichloe typhina (ncbitaxon:5113) - PubMed (17587677) Organism is an endophytic fungus of Phleum prantense
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
fungal metabolite  Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
antifungal agent  An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
ChEBI Ontology
Outgoing Relation(s)
epichlicin (CHEBI:65849) has role antifungal agent (CHEBI:35718)
epichlicin (CHEBI:65849) has role fungal metabolite (CHEBI:76946)
epichlicin (CHEBI:65849) is a homodetic cyclic peptide (CHEBI:24613)
epichlicin (CHEBI:65849) is a macrocycle (CHEBI:51026)
IUPAC Name 
3-[(3R,7S,10R,13S,16S,19S,22S,27aS)-7,13,22-tris(2-amino-2-oxoethyl)-10-(4-hydroxybenzyl)-19-(hydroxymethyl)-1,5,8,11,14,17,20,23-octaoxo-3-undecylhexacosahydro-1H-pyrrolo[2,1-c][1,4,7,10,13,16,19,22]octaazacyclopentacosin-16-yl]propanamide
Registry NumbersSources
Reaxys:11108273Reaxys
Citations