2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777)

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CHEBI:65777 - 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone

ChEBI ID	CHEBI:65777
ChEBI Name	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone
Stars
Definition	A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4', 2-hydroxy benzyl group at position 3' and methoxy group at position 6'. It is isolated from the aerial parts of Ellipeiopsis cherrevensis and exhibits antibacterial, antimalarial and antineoplastic activity.
Last Modified	9 January 2013
Downloads	Molfile

Formula	C23H20O5
Net Charge	0
Average Mass	376.408
Monoisotopic Mass	376.13107
SMILES	COc1cc(O)c(Cc2ccccc2O)c(O)c1C(=O)/C=C/c1ccccc1
InChI	InChI=1S/C23H20O5/c1-28-21-14-20(26)17(13-16-9-5-6-10-18(16)24)23(27)22(21)19(25)12-11-15-7-3-2-4-8-15/h2-12,14,24,26-27H,13H2,1H3/b12-11+
InChIKey	IVKGLRZLTNXWKF-VAWYXSNFSA-N

Species of Metabolite	Component	Source	Comments
Ellipeiopsis cherrevensis (ncbitaxon:672959)	aerial part (BTO:0001658)	PubMed (16833018)

Roles Classification

Biological Roles:

metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria.

antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

Applications:

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

ChEBI Ontology

Outgoing Relation(s)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) has functional parent trans-chalcone (CHEBI:48965)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) has role antibacterial agent (CHEBI:33282)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) has role antimalarial (CHEBI:38068)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) has role antineoplastic agent (CHEBI:35610)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) has role metabolite (CHEBI:25212)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) is a chalcones (CHEBI:23086)
	2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone (CHEBI:65777) is a resorcinols (CHEBI:33572)

IUPAC Name
(2E)-1-[2,4-dihydroxy-3-(2-hydroxybenzyl)-6-methoxyphenyl]-3-phenylprop-2-en-1-one

Registry Numbers	Sources
Reaxys:4564762	Reaxys

Citations