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CHEBI:65672 - cratoxyarborenone B

ChEBI IDCHEBI:65672
ChEBI Namecratoxyarborenone B
Stars
DefinitionA member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 5 and 7 and two isoprenyl groups at positions 2 and 8 respectively. It is isolated from Cratoxylum Sumatranum and exhibits cytotoxicity towards the KB (human oral epidermoid) cancer cell line.
Last Modified18 December 2012
DownloadsMolfile
FormulaC23H24O6
Net Charge0
Average Mass396.439
Monoisotopic Mass396.15729
SMILESCC(C)=CCc1c(O)cc2oc3c(O)cc(O)c(CC=C(C)C)c3c(=O)c2c1O
InChIInChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-17(26)23-19(13)22(28)20-18(29-23)10-16(25)14(21(20)27)8-6-12(3)4/h5-6,9-10,24-27H,7-8H2,1-4H3
InChIKeyAVGUAOZYPIBDIZ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Cratoxylum Sumatranum (IPNI:433074-1)
leaf (BTO:0000713) PubMed (11908969)
twig (BTO:0001411) PubMed (11908969)
stem (BTO:0001300) PubMed (11908969) Previous component: stem bark;
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
cratoxyarborenone B (CHEBI:65672) has role antineoplastic agent (CHEBI:35610)
cratoxyarborenone B (CHEBI:65672) has role metabolite (CHEBI:25212)
cratoxyarborenone B (CHEBI:65672) is a polyphenol (CHEBI:26195)
cratoxyarborenone B (CHEBI:65672) is a xanthones (CHEBI:51149)
IUPAC Name 
1,3,5,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Synonym  Source
1,3,5,7-tetrahydroxy-2,8-diisoprenylxanthoneChEBI
Registry NumbersSources
Reaxys:9094709Reaxys
Citations