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CHEBI:65519 - brasixanthone B

ChEBI IDCHEBI:65519
ChEBI Namebrasixanthone B
Stars
DefinitionA member of the class of pyranoxanthones that is 2H,6H-pyrano[3,2-b]xanthen-6-one substituted by hydroxy, geminal methyl and a prenyl group at positions 5, 8, 2 and 12 respectively. It is isolated from the stem bark of Calophyllum brasiliense and exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation in Raji cells.
Last Modified27 November 2012
DownloadsMolfile
FormulaC23H22O5
Net Charge0
Average Mass378.424
Monoisotopic Mass378.14672
SMILESCC(C)=CCc1c2c(c(O)c3c(=O)c4cc(O)ccc4oc13)C=CC(C)(C)O2
InChIInChI=1S/C23H22O5/c1-12(2)5-7-15-21-14(9-10-23(3,4)28-21)19(25)18-20(26)16-11-13(24)6-8-17(16)27-22(15)18/h5-6,8-11,24-25H,7H2,1-4H3
InChIKeyBFPCRQCNDMJVOT-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Calophyllum brasiliense (IPNI:427115-1) stem (BTO:0001300) PubMed (11908963) Previous component: stem bark;
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
brasixanthone B (CHEBI:65519) has role antineoplastic agent (CHEBI:35610)
brasixanthone B (CHEBI:65519) has role metabolite (CHEBI:25212)
brasixanthone B (CHEBI:65519) is a polyphenol (CHEBI:26195)
brasixanthone B (CHEBI:65519) is a pyranoxanthones (CHEBI:71238)
Synonyms  Source
cudraxanthone QChEBI
5,8-dihydroxy-2,2-dimethyl-12-(3-methylbut-2-en-1-yl)-2H,6H-pyrano[3,2-b]xanthen-6-oneIUPAC
Manual XrefsDatabases
8537718ChemSpider
Registry NumbersSources
Reaxys:8800172Reaxys
Citations