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CHEBI:6532 - loperamide
| Formula | C29H33ClN2O2 |
| Net Charge | 0 |
| Average Mass | 477.048 |
| Monoisotopic Mass | 476.22306 |
| SMILES | CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 |
| InChI | InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 |
| InChIKey | RDOIQAHITMMDAJ-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
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| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. mu-opioid receptor agonist A compound that exhibits agonist activity at the μ-opioid receptor. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. |
| Applications: | dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antidiarrhoeal drug Any drug found useful in the symptomatic treatment of diarrhoea. mu-opioid receptor agonist A compound that exhibits agonist activity at the μ-opioid receptor. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| loperamide (CHEBI:6532) has role analgesic (CHEBI:35480) |
| loperamide (CHEBI:6532) has role antibacterial agent (CHEBI:33282) |
| loperamide (CHEBI:6532) has role anticoronaviral agent (CHEBI:149553) |
| loperamide (CHEBI:6532) has role antidiarrhoeal drug (CHEBI:55323) |
| loperamide (CHEBI:6532) has role antineoplastic agent (CHEBI:35610) |
| loperamide (CHEBI:6532) has role dermatologic drug (CHEBI:50177) |
| loperamide (CHEBI:6532) has role μ-opioid receptor agonist (CHEBI:55322) |
| loperamide (CHEBI:6532) is a monocarboxylic acid amide (CHEBI:29347) |
| loperamide (CHEBI:6532) is a monochlorobenzenes (CHEBI:83403) |
| loperamide (CHEBI:6532) is a piperidines (CHEBI:26151) |
| loperamide (CHEBI:6532) is a tertiary alcohol (CHEBI:26878) |
| loperamide (CHEBI:6532) is conjugate base of loperamide(1+) (CHEBI:86969) |
| Incoming Relation(s) |
| loperamide(1+) (CHEBI:86969) is conjugate acid of loperamide (CHEBI:6532) |
| IUPAC Name |
|---|
| 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide |
| INNs | Source |
|---|---|
| loperamida | ChemIDplus |
| loperamide | ChemIDplus |
| loperamidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| Loperamide | KEGG COMPOUND |
| lopéramide | WHO MedNet |
| Manual Xrefs | Databases |
|---|---|
| 1599 | DrugCentral |
| C07080 | KEGG COMPOUND |
| D08144 | KEGG DRUG |
| DB00836 | DrugBank |
| FR2100711 | Patent |
| HMDB0004999 | HMDB |
| Loperamide | Wikipedia |
| LSM-3365 | LINCS |
| US3714159 | Patent |
| Registry Numbers | Sources |
|---|---|
| Reaxys:1558273 | Reaxys |
| CAS:53179-11-6 | KEGG COMPOUND |
| CAS:53179-11-6 | ChemIDplus |
| Citations |
|---|