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CHEBI:65311 - corticotropin-releasing hormone
| ChEBI ID | CHEBI:65311 |
| ChEBI Name | corticotropin-releasing hormone |
| Stars | |
| Definition | A family of peptide hormones derived from a 191-membered prehormone, secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. The first full sequence was discovered in sheep, those in rats and humans differ from the ovine sequence by 7 amino acids. |
| Last Modified | 24 July 2012 |
| Submitter | Steve |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | neurotransmitter An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| corticotropin-releasing hormone (CHEBI:65311) has role neurotransmitter (CHEBI:25512) |
| corticotropin-releasing hormone (CHEBI:65311) is a biomacromolecule (CHEBI:33694) |
| corticotropin-releasing hormone (CHEBI:65311) is a peptide hormone (CHEBI:25905) |
| corticotropin-releasing hormone (CHEBI:65311) is a polypeptide (CHEBI:15841) |
| Incoming Relation(s) |
| corticotropin-releasing hormone (human) (CHEBI:65312) is a corticotropin-releasing hormone (CHEBI:65311) |
| corticotropin-releasing hormone (ovine) (CHEBI:65307) is a corticotropin-releasing hormone (CHEBI:65311) |
| Synonyms | Source |
|---|---|
| corticotropin-releasing factor | ChEBI |
| CRH | ChEBI |
| Manual Xrefs | Databases |
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| Corticotropin-releasing_hormone | Wikipedia |
| Citations |
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