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CHEBI:65209 - E-3810 free base
| Formula | C26H25N3O4 |
| Net Charge | 0 |
| Average Mass | 443.503 |
| Monoisotopic Mass | 443.18451 |
| SMILES | CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 |
| InChI | InChI=1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30) |
| InChIKey | CUDVHEFYRIWYQD-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | fibroblast growth factor receptor antagonist An antagonist at the fibroblast growth factor receptor. vascular endothelial growth factor receptor antagonist An antagonist at the vascular endothelial growth factor receptor. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| E-3810 free base (CHEBI:65209) has role antineoplastic agent (CHEBI:35610) |
| E-3810 free base (CHEBI:65209) has role fibroblast growth factor receptor antagonist (CHEBI:63457) |
| E-3810 free base (CHEBI:65209) has role vascular endothelial growth factor receptor antagonist (CHEBI:65207) |
| E-3810 free base (CHEBI:65209) is a aromatic ether (CHEBI:35618) |
| E-3810 free base (CHEBI:65209) is a cyclopropanes (CHEBI:51454) |
| E-3810 free base (CHEBI:65209) is a naphthalenecarboxamide (CHEBI:48739) |
| E-3810 free base (CHEBI:65209) is a primary amino compound (CHEBI:50994) |
| E-3810 free base (CHEBI:65209) is a quinolines (CHEBI:26513) |
| E-3810 free base (CHEBI:65209) is conjugate base of E-3810(1+) (CHEBI:65208) |
| Incoming Relation(s) |
| E-3810(1+) (CHEBI:65208) is conjugate acid of E-3810 free base (CHEBI:65209) |
| IUPAC Name |
|---|
| 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide |
| Synonym | Source |
|---|---|
| E-3810 amine | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:18478470 | Reaxys |