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CHEBI:650657 - ketamine hydrochloride
| Formula | C13H17ClNO.Cl |
| Net Charge | 0 |
| Average Mass | 274.191 |
| Monoisotopic Mass | 273.06872 |
| SMILES | C[NH2+]C1(c2ccccc2Cl)CCCCC1=O.[Cl-] |
| InChI | InChI=1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H |
| InChIKey | VCMGMSHEPQENPE-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anticonvulsant A drug used to prevent seizures or reduce their severity. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. appetite enhancer A drug which increases appetite. vulnerary A drug used in treating and healing of wounds. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| ketamine hydrochloride (CHEBI:650657) has part ketamine (CHEBI:6121) |
| ketamine hydrochloride (CHEBI:650657) has role analgesic (CHEBI:35480) |
| ketamine hydrochloride (CHEBI:650657) has role anticonvulsant (CHEBI:35623) |
| ketamine hydrochloride (CHEBI:650657) has role antidepressant (CHEBI:35469) |
| ketamine hydrochloride (CHEBI:650657) has role antineoplastic agent (CHEBI:35610) |
| ketamine hydrochloride (CHEBI:650657) has role antipsychotic agent (CHEBI:35476) |
| ketamine hydrochloride (CHEBI:650657) has role appetite enhancer (CHEBI:50779) |
| ketamine hydrochloride (CHEBI:650657) has role intravenous anaesthetic (CHEBI:38877) |
| ketamine hydrochloride (CHEBI:650657) has role NMDA receptor antagonist (CHEBI:60643) |
| ketamine hydrochloride (CHEBI:650657) has role vulnerary (CHEBI:73336) |
| ketamine hydrochloride (CHEBI:650657) is a hydrochloride (CHEBI:36807) |
| Incoming Relation(s) |
| esketamine hydrochloride (CHEBI:60800) is a ketamine hydrochloride (CHEBI:650657) |
| IUPAC Names |
|---|
| 1-(2-chlorophenyl)-N-methyl-2-oxocyclohexanaminium chloride |
| 2-(2-chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Synonyms | Source |
|---|---|
| (±)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride | ChemIDplus |
| 2-(o-chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride | ChEBI |
| CI-581 | ChEMBL |
| CL 369 | ChEMBL |
| CL-369 | ChEMBL |
| CN-52,372-2 | ChEMBL |
| Brand Names | Source |
|---|---|
| Ketaject | DrugBank |
| Ketalar | DrugBank |
| Ketanest | DrugBank |
| Ketaset | ChEMBL |
| Citations |
|---|