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CHEBI:64610 - tenocyclidine

ChEBI IDCHEBI:64610
ChEBI Nametenocyclidine
Stars
DefinitionA tertiary amino compound that consists of cyclohexane having piperidin-1-yl and thiophen-2-yl groups attached at position 1. A dissociative anaesthetic drug with halluccinogenic and stimulant effects. Its effects are similar to those of phencyclidine (PCP, an analogue with the thienyl group replaced by phenyl), but it is rather more potent.
Last Modified21 August 2012
SubmitterSteve
DownloadsMolfile
FormulaC15H23NS
Net Charge0
Average Mass249.423
Monoisotopic Mass249.15512
SMILESc1csc(C2(N3CCCCC3)CCCCC2)c1
InChIInChI=1S/C15H23NS/c1-3-9-15(10-4-1,14-8-7-13-17-14)16-11-5-2-6-12-16/h7-8,13H,1-6,9-12H2
InChIKeyJUZZEWSCNBCFRL-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
NMDA receptor antagonist  Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Applications:
hallucinogen  Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
tenocyclidine (CHEBI:64610) has role central nervous system stimulant (CHEBI:35337)
tenocyclidine (CHEBI:64610) has role hallucinogen (CHEBI:35499)
tenocyclidine (CHEBI:64610) has role neuroprotective agent (CHEBI:63726)
tenocyclidine (CHEBI:64610) has role NMDA receptor antagonist (CHEBI:60643)
tenocyclidine (CHEBI:64610) is a piperidines (CHEBI:26151)
tenocyclidine (CHEBI:64610) is a tertiary amino compound (CHEBI:50996)
tenocyclidine (CHEBI:64610) is a thiophenes (CHEBI:26961)
IUPAC Name 
1-[1-(2-thienyl)cyclohexyl]piperidine
INNs  Source
tenocyclidinumChemIDplus
tenocyclidineChemIDplus
tenociclidinaChemIDplus
Synonyms  Source
1-[1-(thiophen-2-yl)cyclohexyl]piperidineChEBI
thienyl cyclohexylpiperidineDrugBank
Manual XrefsDatabases
DB01520DrugBank
TenocyclidineWikipedia
Registry NumbersSources
Reaxys:1246605Reaxys
CAS:21500-98-1ChemIDplus
Citations