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CHEBI:64312 - memantine
| Formula | C12H21N |
| Net Charge | 0 |
| Average Mass | 179.307 |
| Monoisotopic Mass | 179.16740 |
| SMILES | CC12CC3CC(C)(C1)CC(N)(C3)C2 |
| InChI | InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3 |
| InChIKey | BUGYDGFZZOZRHP-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anti-obesity agent Any substance which is used to reduce or control weight. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antiparkinson drug A drug used in the treatment of Parkinson's disease. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| memantine (CHEBI:64312) has parent hydride adamantane (CHEBI:40519) |
| memantine (CHEBI:64312) has role analgesic (CHEBI:35480) |
| memantine (CHEBI:64312) has role anti-obesity agent (CHEBI:74518) |
| memantine (CHEBI:64312) has role antidepressant (CHEBI:35469) |
| memantine (CHEBI:64312) has role antiglaucoma drug (CHEBI:39456) |
| memantine (CHEBI:64312) has role antineoplastic agent (CHEBI:35610) |
| memantine (CHEBI:64312) has role antiparkinson drug (CHEBI:48407) |
| memantine (CHEBI:64312) has role antipsychotic agent (CHEBI:35476) |
| memantine (CHEBI:64312) has role anxiolytic drug (CHEBI:35474) |
| memantine (CHEBI:64312) has role dopaminergic agent (CHEBI:48560) |
| memantine (CHEBI:64312) has role immunosuppressive agent (CHEBI:35705) |
| memantine (CHEBI:64312) has role neuroprotective agent (CHEBI:63726) |
| memantine (CHEBI:64312) has role NMDA receptor antagonist (CHEBI:60643) |
| memantine (CHEBI:64312) is a adamantanes (CHEBI:51339) |
| memantine (CHEBI:64312) is a primary aliphatic amine (CHEBI:17062) |
| memantine (CHEBI:64312) is conjugate base of memantinium(1+) (CHEBI:64325) |
| Incoming Relation(s) |
| memantinium(1+) (CHEBI:64325) is conjugate acid of memantine (CHEBI:64312) |
| IUPAC Name |
|---|
| 3,5-dimethyladamantan-1-amine |
| INNs | Source |
|---|---|
| memantina | DrugBank |
| memantine | KEGG DRUG |
| memantinum | DrugBank |
| Synonyms | Source |
|---|---|
| 1,3-Dimethyl-5-adamantanamine | ChemIDplus |
| 1-Amino-3,5-dimethyladamantane | ChemIDplus |
| 3,5-Dimethyl-1-adamantanamine | NIST Chemistry WebBook |
| 3,5-Dimethyl-1-aminoadamantane | ChEBI |
| 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine | ChemIDplus |
| D-145 | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:2075983 | Reaxys |
| CAS:19982-08-2 | KEGG COMPOUND |
| CAS:19982-08-2 | ChemIDplus |
| CAS:19982-08-2 | NIST Chemistry WebBook |
| Citations |
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