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CHEBI:64164 - N-methylquipazine

ChEBI IDCHEBI:64164
ChEBI NameN-methylquipazine
Stars
ASCII NameN-methylquipazine
DefinitionAn aminoquinoline that consists of quinoline in which the hydrogen at position 2 is substituted by a 4-methylpiperazin-1-yl group. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.
Last Modified6 July 2016
SubmitterSteve
DownloadsMolfile
FormulaC14H17N3
Net Charge0
Average Mass227.311
Monoisotopic Mass227.14225
SMILESCN1CCN(c2ccc3ccccc3n2)CC1
InChIInChI=1S/C14H17N3/c1-16-8-10-17(11-9-16)14-7-6-12-4-2-3-5-13(12)15-14/h2-7H,8-11H2,1H3
InChIKeyHOMWNUXPSJQSSU-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Application:
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
ChEBI Ontology
Outgoing Relation(s)
N-methylquipazine (CHEBI:64164) has role serotonergic agonist (CHEBI:35941)
N-methylquipazine (CHEBI:64164) is a N-alkylpiperazine (CHEBI:46845)
N-methylquipazine (CHEBI:64164) is a N-arylpiperazine (CHEBI:46848)
N-methylquipazine (CHEBI:64164) is a aminoquinoline (CHEBI:36709)
Incoming Relation(s)
N-methylquipazine dimaleate (CHEBI:64162) has part N-methylquipazine (CHEBI:64164)
Manual XrefsDatabases
LSM-3379LINCS
Registry NumbersSources
Reaxys:887071Reaxys
Citations