EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:63791 - lenalidomide

Default Structure
ChEBI IDCHEBI:63791
ChEBI Namelenalidomide
Stars
DefinitionA dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-α.
Last Modified22 February 2017
DownloadsMolfile
FormulaC13H13N3O3
Net Charge0
Average Mass259.265
Monoisotopic Mass259.09569
SMILESNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O
InChIInChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antifibrotic agent  Any agent which acts to reduce fibrosis.
angiogenesis inhibitor  An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
ChEBI Ontology
Outgoing Relation(s)
lenalidomide (CHEBI:63791) has role analgesic (CHEBI:35480)
lenalidomide (CHEBI:63791) has role angiogenesis inhibitor (CHEBI:48422)
lenalidomide (CHEBI:63791) has role anti-anaemic agent (CHEBI:75835)
lenalidomide (CHEBI:63791) has role anti-HIV agent (CHEBI:64946)
lenalidomide (CHEBI:63791) has role antifibrotic agent (CHEBI:233423)
lenalidomide (CHEBI:63791) has role antineoplastic agent (CHEBI:35610)
lenalidomide (CHEBI:63791) has role immunomodulator (CHEBI:50846)
lenalidomide (CHEBI:63791) is a aromatic amine (CHEBI:33860)
lenalidomide (CHEBI:63791) is a dicarboximide (CHEBI:35356)
lenalidomide (CHEBI:63791) is a isoindoles (CHEBI:24897)
lenalidomide (CHEBI:63791) is a piperidones (CHEBI:48589)
IUPAC Name 
3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
INNs  Source
lenalidomidaWHO MedNet
lenalidomideKEGG DRUG
Synonyms  Source
1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindolineChEBI
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneChemIDplus
CC-5013ChEMBL
CDC-501ChEMBL
NSC-747972ChEMBL
SYP-1512ChEMBL
Brand Names  Source
Lenalidomide accordChEMBL
Lenalidomide mylanChEMBL
RevlimidKEGG DRUG
Manual XrefsDatabases
3317DrugCentral
D04687KEGG DRUG
DB00480DrugBank
LenalidomideWikipedia
LSM-6187LINCS
Registry NumbersSources
Reaxys:8335210Reaxys
CAS:191732-72-6ChemIDplus
Citations