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CHEBI:63791 - lenalidomide

Default Structure
ChEBI IDCHEBI:63791
ChEBI Namelenalidomide
Stars
DefinitionA dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-α.
Last Modified22 February 2017
DownloadsMolfile
FormulaC13H13N3O3
Net Charge0
Average Mass259.265
Monoisotopic Mass259.09569
SMILESNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O
InChIInChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
Applications:
angiogenesis inhibitor  An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
lenalidomide (CHEBI:63791) has role angiogenesis inhibitor (CHEBI:48422)
lenalidomide (CHEBI:63791) has role antineoplastic agent (CHEBI:35610)
lenalidomide (CHEBI:63791) has role immunomodulator (CHEBI:50846)
lenalidomide (CHEBI:63791) is a aromatic amine (CHEBI:33860)
lenalidomide (CHEBI:63791) is a dicarboximide (CHEBI:35356)
lenalidomide (CHEBI:63791) is a isoindoles (CHEBI:24897)
lenalidomide (CHEBI:63791) is a piperidones (CHEBI:48589)
IUPAC Name 
3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
INN  Source
lenalidomideKEGG DRUG
Synonyms  Source
1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindolineChEBI
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneChemIDplus
Brand Name  Source
RevlimidKEGG DRUG
Manual XrefsDatabases
3317DrugCentral
D04687KEGG DRUG
DB00480DrugBank
LenalidomideWikipedia
LSM-6187LINCS
Registry NumbersSources
Reaxys:8335210Reaxys
CAS:191732-72-6ChemIDplus
Citations