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CHEBI:6375 - lansoprazole

ChEBI IDCHEBI:6375
ChEBI Namelansoprazole
Stars
Last Modified22 February 2017
DownloadsMolfile
FormulaC16H14F3N3O2S
Net Charge0
Average Mass369.368
Monoisotopic Mass369.07588
SMILESCc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2n1
InChIInChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)
InChIKeyMJIHNNLFOKEZEW-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor  An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors.
Application:
anti-ulcer drug  One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
ChEBI Ontology
Outgoing Relation(s)
lansoprazole (CHEBI:6375) has role anti-ulcer drug (CHEBI:49201)
lansoprazole (CHEBI:6375) has role EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200)
lansoprazole (CHEBI:6375) is a benzimidazoles (CHEBI:22715)
lansoprazole (CHEBI:6375) is a pyridines (CHEBI:26421)
lansoprazole (CHEBI:6375) is a sulfoxide (CHEBI:22063)
IUPAC Name 
2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
INNs  Source
lansoprazolChemIDplus
lansoprazolumChemIDplus
Synonym  Source
AG 1749DrugBank
Brand Names  Source
PrevacidDrugBank
BamaliteDrugBank
LanzolDrugBank
LanzopralDrugBank
LanzulChEBI
LimpidexDrugBank
Manual XrefsDatabases
D00355KEGG DRUG
EP174726Patent
US4628098Patent
LansoprazoleWikipedia
DB00448DrugBank
LSM-5064LINCS
1547DrugCentral
Registry NumbersSources
Beilstein:4333393Beilstein
CAS:103577-45-3ChemIDplus