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CHEBI:63638 - vigabatrin

Default Structure
ChEBI IDCHEBI:63638
ChEBI Namevigabatrin
Stars
DefinitionA γ-amino acid having a γ-vinyl GABA structure. It is an irreversible inhibitor of γ-aminobutyric 664 acid transaminase
Secondary ChEBI IDCHEBI:9979
Last Modified22 February 2017
DownloadsMolfile
FormulaC6H11NO2
Net Charge0
Average Mass129.159
Monoisotopic Mass129.07898
SMILESC=CC(N)CCC(=O)O
InChIInChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
InChIKeyPJDFLNIOAUIZSL-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
anti-obesity agent  Any substance which is used to reduce or control weight.
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor  An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19).
Applications:
anticonvulsant  A drug used to prevent seizures or reduce their severity.
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
ChEBI Ontology
Outgoing Relation(s)
vigabatrin (CHEBI:63638) has role anti-obesity agent (CHEBI:74518)
vigabatrin (CHEBI:63638) has role anticonvulsant (CHEBI:35623)
vigabatrin (CHEBI:63638) has role antispasmodic drug (CHEBI:53784)
vigabatrin (CHEBI:63638) has role EC 2.6.1.19 (4-aminobutyrate—2-oxoglutarate transaminase) inhibitor (CHEBI:63674)
vigabatrin (CHEBI:63638) is a γ-amino acid (CHEBI:33707)
IUPAC Name 
4-aminohex-5-enoic acid
INNs  Source
vigabatrinChemIDplus
vigabatrinaChemIDplus
vigabatrineChemIDplus
vigabatrinumChemIDplus
Synonyms  Source
4-Amino-5-hexenoic acidChemIDplus
5-hexenoic acid, 4-amino-ChEMBL
CPP-109ChEMBL
gamma-vinyl GABAChEBI
gamma-Vinyl GABAChemIDplus
Gamma vinyl gabaChEMBL
Brand Name  Source
KigabeqChEMBL
Manual XrefsDatabases
2819DrugCentral
C07500KEGG COMPOUND
D00535KEGG DRUG
DB01080DrugBank
LSM-4959LINCS
US3960927Patent
VigabatrinWikipedia
Registry NumbersSources
CAS:60643-86-9ChemIDplus
CAS:60643-86-9KEGG COMPOUND
Citations