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CHEBI:63638 - vigabatrin

ChEBI IDCHEBI:63638
ChEBI Namevigabatrin
Stars
DefinitionA γ-amino acid having a γ-vinyl GABA structure. It is an irreversible inhibitor of γ-aminobutyric 664 acid transaminase
Secondary ChEBI IDCHEBI:9979
Last Modified22 February 2017
DownloadsMolfile
FormulaC6H11NO2
Net Charge0
Average Mass129.159
Monoisotopic Mass129.07898
SMILESC=CC(N)CCC(=O)O
InChIInChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
InChIKeyPJDFLNIOAUIZSL-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Role:
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor  An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19).
Application:
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
vigabatrin (CHEBI:63638) has role anticonvulsant (CHEBI:35623)
vigabatrin (CHEBI:63638) has role EC 2.6.1.19 (4-aminobutyrate—2-oxoglutarate transaminase) inhibitor (CHEBI:63674)
vigabatrin (CHEBI:63638) is a γ-amino acid (CHEBI:33707)
IUPAC Name 
4-aminohex-5-enoic acid
INNs  Source
vigabatrinumChemIDplus
vigabatrinChemIDplus
vigabatrineChemIDplus
vigabatrinaChemIDplus
Synonyms  Source
4-Amino-5-hexenoic acidChemIDplus
gamma-Vinyl GABAChemIDplus
GVGChemIDplus
γ-vinyl GABAChEBI
gamma-vinyl GABAChEBI
γ-vinyl-γ-aminobutyric acidChEBI
Manual XrefsDatabases
C07500KEGG COMPOUND
DB01080DrugBank
D00535KEGG DRUG
VigabatrinWikipedia
US3960927Patent
LSM-4959LINCS
2819DrugCentral
Registry NumbersSources
CAS:60643-86-9KEGG COMPOUND
CAS:60643-86-9ChemIDplus
Citations