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CHEBI:63624 - telbivudine

ChEBI IDCHEBI:63624
ChEBI Nametelbivudine
Stars
DefinitionA pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.
Last Modified22 February 2017
DownloadsMolfile
FormulaC10H14N2O5
Net Charge0
Average Mass242.231
Monoisotopic Mass242.09027
SMILESCc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)nc1=O
InChIInChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
InChIKeyIQFYYKKMVGJFEH-CSMHCCOUSA-N
Wikipedia
Roles Classification
Biological Roles:
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor  A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
Application:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
ChEBI Ontology
Outgoing Relation(s)
telbivudine (CHEBI:63624) has functional parent thymine (CHEBI:17821)
telbivudine (CHEBI:63624) has role antiviral drug (CHEBI:36044)
telbivudine (CHEBI:63624) has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor (CHEBI:59897)
telbivudine (CHEBI:63624) is a pyrimidine 2'-deoxyribonucleoside (CHEBI:19255)
telbivudine (CHEBI:63624) is enantiomer of thymidine (CHEBI:17748)
Incoming Relation(s)
thymidine (CHEBI:17748) is enantiomer of telbivudine (CHEBI:63624)
IUPAC Name 
1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
INN  Source
telbivudineKEGG DRUG
Synonyms  Source
Beta-l-thymidineDrugBank
L-DTDrugBank
L-thymidineDrugBank
LDTDrugBank
L-deoxythymidineDrugBank
EpavudineDrugBank
Manual XrefsDatabases
D06675KEGG DRUG
DB01265DrugBank
TelbivudineWikipedia
4220DrugCentral
Registry NumbersSources
Reaxys:754297Reaxys
CAS:3424-98-4ChemIDplus
Citations