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CHEBI:63622 - sotalol
| Formula | C12H20N2O3S |
| Net Charge | 0 |
| Average Mass | 272.370 |
| Monoisotopic Mass | 272.11946 |
| SMILES | CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 |
| InChI | InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 |
| InChIKey | ZBMZVLHSJCTVON-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sotalol (CHEBI:63622) has role anti-arrhythmia drug (CHEBI:38070) |
| sotalol (CHEBI:63622) has role environmental contaminant (CHEBI:78298) |
| sotalol (CHEBI:63622) has role xenobiotic (CHEBI:35703) |
| sotalol (CHEBI:63622) has role β-adrenergic antagonist (CHEBI:35530) |
| sotalol (CHEBI:63622) is a ethanolamines (CHEBI:23981) |
| sotalol (CHEBI:63622) is a secondary alcohol (CHEBI:35681) |
| sotalol (CHEBI:63622) is a secondary amino compound (CHEBI:50995) |
| sotalol (CHEBI:63622) is a sulfonamide (CHEBI:35358) |
| sotalol (CHEBI:63622) is conjugate base of sotalol(1+) (CHEBI:63647) |
| Incoming Relation(s) |
| sotalol(1+) (CHEBI:63647) is conjugate acid of sotalol (CHEBI:63622) |
| IUPAC Name |
|---|
| N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide |
| INNs | Source |
|---|---|
| sotalol | ChemIDplus |
| sotalolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| Sotalol | KEGG COMPOUND |
| 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide | ChemIDplus |
| β-cardone | ChemIDplus |
| Citations |
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