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CHEBI:63620 - rasagiline

ChEBI IDCHEBI:63620
ChEBI Namerasagiline
Stars
DefinitionAn indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.
Last Modified2 May 2013
DownloadsMolfile
FormulaC12H13N
Net Charge0
Average Mass171.243
Monoisotopic Mass171.10480
SMILESC#CCN[C@@H]1CCc2ccccc21
InChIInChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
InChIKeyRUOKEQAAGRXIBM-GFCCVEGCSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
EC 1.4.3.4 (monoamine oxidase) inhibitor  An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
Application:
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
rasagiline (CHEBI:63620) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
rasagiline (CHEBI:63620) has role neuroprotective agent (CHEBI:63726)
rasagiline (CHEBI:63620) is a indanes (CHEBI:46940)
rasagiline (CHEBI:63620) is a secondary amine (CHEBI:32863)
rasagiline (CHEBI:63620) is a terminal acetylenic compound (CHEBI:73477)
IUPAC Name 
(1R)-N-(prop-2-yn-1-yl)indan-1-amine
INN  Source
rasagilineKEGG DRUG
Synonyms  Source
(1R)-N-propargylindan-1-amineChEBI
(R)-indan-1-yl-prop-2-ynyl-amineChEBI
RASDrugBank
(R)-N-2-Propynyl-1-indanamineChemIDplus
Manual XrefsDatabases
D08469KEGG DRUG
DB01367DrugBank
RasagilineWikipedia
Registry NumbersSources
Reaxys:9194207Reaxys
CAS:136236-51-6ChemIDplus
CAS:136236-51-6KEGG DRUG
Citations