CHEBI:63607 - linezolid

ChEBI IDCHEBI:63607
ChEBI Namelinezolid
Stars
DefinitionAn organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.
Secondary ChEBI IDCHEBI:6477
Last Modified22 February 2017
DownloadsMolfile
FormulaC16H20FN3O4
Net Charge0
Average Mass337.351
Monoisotopic Mass337.14378
SMILESCC(=O)NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1
InChIInChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
InChIKeyTYZROVQLWOKYKF-ZDUSSCGKSA-N
Wikipedia
Roles Classification
Biological Roles:
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antibacterial drug  A drug used to treat or prevent bacterial infections.
Application:
antibacterial drug  A drug used to treat or prevent bacterial infections.
ChEBI Ontology
Outgoing Relation(s)
linezolid (CHEBI:63607) has role antibacterial drug (CHEBI:36047)
linezolid (CHEBI:63607) has role protein synthesis inhibitor (CHEBI:48001)
linezolid (CHEBI:63607) is a acetamides (CHEBI:22160)
linezolid (CHEBI:63607) is a morpholines (CHEBI:38785)
linezolid (CHEBI:63607) is a organofluorine compound (CHEBI:37143)
linezolid (CHEBI:63607) is a oxazolidinone (CHEBI:55374)
IUPAC Name 
N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
INN  Source
linezolidKEGG DRUG
Synonyms  Source
LinezolidKEGG COMPOUND
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideChemIDplus
Manual XrefsDatabases
1584DrugCentral
C08146KEGG COMPOUND
D00947KEGG DRUG
DB00601DrugBank
LinezolidWikipedia
LSM-5750LINCS
US5688792Patent
WO957271Patent
ZLDPDBeChem
Registry NumbersSources
Reaxys:7496939Reaxys
CAS:165800-03-3ChemIDplus
CAS:165800-03-3KEGG COMPOUND
Citations