EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:63486 - 8-azaguanine
| Formula | C4H4N6O |
| Net Charge | 0 |
| Average Mass | 152.117 |
| Monoisotopic Mass | 152.04466 |
| SMILES | Nc1nc(=O)c2nnnc2n1 |
| InChI | InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11) |
| InChIKey | LPXQRXLUHJKZIE-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of purine nucleoside phosphorylase (EC 2.4.2.1). antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| 8-azaguanine (CHEBI:63486) has role antimetabolite (CHEBI:35221) |
| 8-azaguanine (CHEBI:63486) has role antineoplastic agent (CHEBI:35610) |
| 8-azaguanine (CHEBI:63486) has role EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor (CHEBI:63090) |
| 8-azaguanine (CHEBI:63486) is a nucleobase analogue (CHEBI:67142) |
| 8-azaguanine (CHEBI:63486) is a triazolopyrimidines (CHEBI:48435) |
| Incoming Relation(s) |
| 8-aza-cAMP (CHEBI:84609) has functional parent 8-azaguanine (CHEBI:63486) |
| IUPAC Name |
|---|
| 5-amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one |
| Synonyms | Source |
|---|---|
| 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one | ChEBI |
| 5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one | ChemIDplus |
| 5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one | ChemIDplus |
| 5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol | NIST Chemistry WebBook |
| 5-Amino-1H-v-triazolo(d)pyrimidin-7-ol | ChemIDplus |
| 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine | ChemIDplus |
| Citations |
|---|